| 词条 | 2-Pyrrolidone |
| 释义 |
| Verifiedfields = changed | Watchedfields = changed | verifiedrevid = 477215634 | Name = 2-Pyrrolidone | ImageFileL1 = 2-Pyrrolidone.png | ImageNameL1 = 2-Pyrrolidone | ImageFileR1 = Pyrrolidone-3D-vdW.png | PIN = Pyrrolidin-2-one | OtherNames = 2-Pyrrolidone 2-Pyrrolidinone |Section1={{Chembox Identifiers | ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}} | ChemSpiderID = 11530 | PubChem = 12025 | InChI = 1/C4H7NO/c6-4-2-1-3-5-4/h1-3H2,(H,5,6) | InChIKey = HNJBEVLQSNELDL-UHFFFAOYAP | ChEMBL_Ref = {{ebicite|correct|EBI}} | EINECS = 210-483-1 | ChEMBL = 276849 | StdInChI_Ref = {{stdinchicite|correct|chemspider}} | StdInChI = 1S/C4H7NO/c6-4-2-1-3-5-4/h1-3H2,(H,5,6) | StdInChIKey_Ref = {{stdinchicite|correct|chemspider}} | StdInChIKey = HNJBEVLQSNELDL-UHFFFAOYSA-N | CASNo_Ref = {{cascite|correct|CAS}} | CASNo = 616-45-5 | ChEBI_Ref = {{ebicite|correct|EBI}} | ChEBI = 36592 | UNII_Ref = {{fdacite|correct|FDA}} | UNII = KKL5D39EOL | SMILES = O=C1NCCC1 }} |Section2={{Chembox Properties | C=4 | H=7 | N=1 | O=1 | Density = 1.116 g/cm3[1] | MeltingPtC = 25 | MeltingPt_ref = [2] | BoilingPtC = 245 | BoilingPt_ref = [1] |Section7={{Chembox Hazards | ExternalSDS = [https://www.sciencelab.com/msds.php?msdsId=9924777 ScienceLab.com] | NFPA-H = 2 | NFPA-F = 1 | NFPA-R = 0 | NFPA-S = | FlashPt = {{convert|129|C|F}} (open cup)[1] {{convert|138|C|F}} (closed cup)[2]}} }}2-Pyrrolidone is an organic compound consisting of a 5-membered lactam, making it the simplest γ-lactam. It is a colorless liquid that is miscible with water and most common organic solvents.[3] It is produced industrially by treating butyrolactone with ammonia. Alternative routes include the partial hydrogenation of succinimide and the carbonylation of allylamine with methyl amine. 2-Pyrrolidone is an intermediate in the production of vinylpyrrolidone and the drug piracetam.[3] UsesA variety of pharmaceutical drugs are 2-pyrrolidone derivatives including:
2-pyrrolidone is used in inkjet cartridges.[4] Safety2-pyrrolidone is an eye irritant.[4] See also
References1. ^1 2 Merck Index, 11th Edition, 8027 2. ^1 {{GESTIS|ZVG=490258}} 3. ^1 Albrecht Ludwig Harreus, R. Backes, J.-O. Eichler, R. Feuerhake, C. Jäkel, U. Mahn, R. Pinkos, R. Vogelsang"2-Pyrrolidone" in Ullmann's Encyclopedia of Industrial Chemistry, Wiley-VCH, 2011, Weinheim. {{DOI|10.1002/14356007.a22_457.pub2}} 4. ^1 {{cite web|title=Safety Data Sheet|url=http://www.hp.com/hpinfo/globalcitizenship/environment/productdata/Countries/gb/ij_ch562series_gb_eng_v14.pdf|website=HP website|publisher=HP|accessdate=11 October 2014|format=PDF|date=7 October 2014}} External links
2 : Amide solvents|Pyrrolidones |
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