“3alpha-hydroxyglycyrrhetinate dehydrogenase”的意思、由来-开放百科全书

词条

3alpha-hydroxyglycyrrhetinate dehydrogenase

释义

References

{{enzyme
| Name = 3-alpha-hydroxyglycyrrhetinate dehydrogenase
| EC_number = 1.1.1.230
| CAS_number = 114308-07-5
| IUBMB_EC_number = 1/1/1/230
| GO_code = 0047032
| image =
| width =
| caption =
}}

In enzymology, a 3alpha-hydroxyglycyrrhetinate dehydrogenase ({{EC number|1.1.1.230}}) is an enzyme that catalyzes the chemical reaction

3alpha-hydroxyglycyrrhetinate + NADP⁺ 3-oxoglycyrrhetinate + NADPH + H⁺

Thus, the two substrates of this enzyme are 3alpha-hydroxyglycyrrhetinate and NADP⁺, whereas its 3 products are 3-oxoglycyrrhetinate, NADPH, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD⁺ or NADP⁺ as acceptor. The systematic name of this enzyme class is 3alpha-hydroxyglycyrrhetinate:NADP⁺ 3-oxidoreductase.

References

{{cite journal | vauthors = Akao T, Akao T, Hattori M, Namba T, Kobashi K | date = March 1988 | title = Purification and properties of 3 alpha-hydroxyglycyrrhetinate dehydrogenase of Clostridium innocuum from human intestine | journal = J. Biochem. | volume = 103| pages = 504–7 | pmid = 3164718 | issue = 3 }}

3 : EC 1.1.1|NADPH-dependent enzymes|Enzymes of unknown structure

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