“3beta(or 20alpha)-hydroxysteroid dehydrogenase”的意思、由来-开放百科全书

词条

3beta(or 20alpha)-hydroxysteroid dehydrogenase

释义

References

{{enzyme
| Name = 3β(or 20α)-hydroxysteroid dehydrogenase
| EC_number = 1.1.1.210
| IUBMB_EC_number = 1/1/1/210
| CAS_number= 82869-26-9
| GO_code = 0047024
}}

In enzymology, a 3-β(or 20-α)-hydroxysteroid dehydrogenase ({{EC number|1.1.1.210}}) is an enzyme that catalyzes the chemical reaction

5α-androstan-3β,17β-diol + NADP⁺ 17β-hydroxy-5α-androstan-3-one + NADPH + H⁺

This enzyme possesses the combined activities of the 3-β-hydroxysteroid dehydrogenase/Δ-5-4 isomerase and 20-α-hydroxysteroid dehydrogenase enzymes.^[1]

References

1. ^{{cite journal |vauthors=Sharaf MA, Sweet F | title = Dual activity at an enzyme active site: 3 beta,20 alpha-hydroxysteroid oxidoreductase from fetal blood | journal = Biochemistry | volume = 21 | issue = 19 | pages = 4615–20 |date=September 1982 | pmid = 6958329 | doi = 10.1021/bi00262a016| url = | issn = }}

3 : EC 1.1.1|NADPH-dependent enzymes|Enzymes of unknown structure

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