“3-hydroxyoctanoyl-(acyl-carrier-protein) dehydratase”的意思、由来-开放百科全书

词条

3-hydroxyoctanoyl-(acyl-carrier-protein) dehydratase

释义

References

{{enzyme
| Name = 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase
| EC_number = 4.2.1.59
| CAS_number = 9030-85-7
| IUBMB_EC_number = 4/2/1/59
| GO_code = 0047451
| image =
| width =
| caption =
}}

In enzymology, a 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase ({{EC number|4.2.1.59}}) is an enzyme that catalyzes the chemical reaction

(3R)-3-hydroxyoctanoyl-[acyl-carrier-protein] oct-2-enoyl-[acyl-carrier-protein] + H₂O

Hence, this enzyme has one substrate, (3R)-3-hydroxyoctanoyl-(acyl-carrier-protein), and two products, oct-2-enoyl-[acyl-carrier-protein] and H₂O.

This enzyme belongs to the family of lyases, specifically the hydro-lyases, which cleave carbon-oxygen bonds. The systematic name of this enzyme class is (3R)-3-hydroxyoctanoyl-[acyl-carrier-protein] hydro-lyase (oct-2-enoyl-[acyl-carrier protein]-forming). Other names in common use include D-3-hydroxyoctanoyl-[acyl carrier protein] dehydratase, D-3-hydroxyoctanoyl-acyl carrier protein dehydratase, beta-hydroxyoctanoyl-acyl carrier protein dehydrase, beta-hydroxyoctanoyl thioester dehydratase, beta-hydroxyoctanoyl-ACP-dehydrase, and (3R)-3-hydroxyoctanoyl-[acyl-carrier-protein] hydro-lyase.

References

{{cite journal | vauthors = Mizugaki M, Swindell AC, Wakil SJ | date = 1968 | title = Intermediate- and long-chain beta-hydroxyacyl-ACP dehydrases from E coli fatty acid synthetase | journal = Biochem. Biophys. Res. Commun. | volume = 33 | pages = 520–7 | pmid = 4881058 | doi = 10.1016/0006-291X(68)90607-4 | issue = 3 }}

2 : EC 4.2.1|Enzymes of unknown structure

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