“3-(imidazol-5-yl)lactate dehydrogenase”的意思、由来-开放百科全书

词条

3-(imidazol-5-yl)lactate dehydrogenase

释义

References

{{enzyme
| Name = 3-(imidazol-5-yl)lactate dehydrogenase
| EC_number = 1.1.1.111
| CAS_number = 37250-42-3
| IUBMB_EC_number = 1/1/1/111
| GO_code = 0019155
| image =
| width =
| caption =
}}

In enzymology, a 3-(imidazol-5-yl)lactate dehydrogenase ({{EC number|1.1.1.111}}) is an enzyme that catalyzes the chemical reaction

(S)-3-(imidazol-5-yl)lactate + NAD(P)+ 3-(imidazol-5-yl)pyruvate + NAD(P)H + H⁺

The 3 substrates of this enzyme are (S)-3-(imidazol-5-yl)lactate, NAD⁺, and NADP⁺, whereas its 4 products are 3-(imidazol-5-yl)pyruvate, NADH, NADPH, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD⁺ or NADP⁺ as acceptor. The systematic name of this enzyme class is (S)-3-(imidazol-5-yl)lactate:NAD(P)⁺ oxidoreductase. This enzyme is also called imidazol-5-yl lactate dehydrogenase.

References

{{cite journal | vauthors = Coote JG, Hassall H | title = The role of imidazol-5-yl-lactate-nicotinamide-adenine dinucleotide phosphate oxidoreductase and histidine-2-oxoglutarate aminotransferase in the degradation of imidazol-5-yl-lactate by Pseudomonas acidovorans | journal = The Biochemical Journal | volume = 111 | issue = 2 | pages = 237–9 | date = January 1969 | pmid = 4303364 | pmc = 1187811 }}
{{cite journal | vauthors = Cortese R, Brevet J, Hedegaard J, Roche J | title = [Identification and purification of an alpha-ketoacid aromatic reductase of Escherichia coli B] | language = French | journal = Comptes Rendus des Séances de la Société de Biologie et de ses Filiales | volume = 162 | issue = 2 | pages = 390–5 | year = 1968 | pmid = 4237631 }}

4 : EC 1.1.1|NADPH-dependent enzymes|NADH-dependent enzymes|Enzymes of unknown structure

随便看

开放百科全书收录14589846条英语、德语、日语等多语种百科知识，基本涵盖了大多数领域的百科知识，是一部内容自由、开放的电子版国际百科全书。