“3-oxoacyl-(acyl-carrier-protein) reductase (NADH)”的意思、由来-开放百科全书

词条

3-oxoacyl-(acyl-carrier-protein) reductase (NADH)

释义

References

{{enzyme
| Name = 3-oxoacyl-[acyl-carrier-protein] reductase (NADH)
| EC_number = 1.1.1.212
| CAS_number = 82047-86-7
| IUBMB_EC_number = 1/1/1/212
| GO_code = 0047025
| image =
| width =
| caption =
}}

In enzymology, a 3-oxoacyl-[acyl-carrier-protein] reductase (NADH) ({{EC number|1.1.1.212}}) is an enzyme that catalyzes the chemical reaction

(3R)-3-hydroxyacyl-[acyl-carrier-protein] + NAD⁺ 3-oxoacyl-[acyl-carrier-protein] + NADH + H⁺

Thus, the two substrates of this enzyme are (3R)-3-hydroxyacyl-[acyl-carrier-protein] and NAD⁺, whereas its 3 products are 3-oxoacyl-[acyl-carrier-protein], NADH, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD⁺ or NADP⁺ as acceptor. The systematic name of this enzyme class is (3R)-3-hydroxyacyl-[acyl-carrier-protein]:NAD⁺ oxidoreductase. Other names in common use include 3-oxoacyl-[acyl carrier protein] (reduced nicotinamide adenine, dinucleotide) reductase, and 3-oxoacyl-[acyl-carrier-protein] reductase (NADH).

References

{{cite journal | doi = 10.1111/j.1432-1033.1982.tb06568.x |vauthors=Caughey I, Kekwick RG | date = 1982 | title = The characteristics of some components of the fatty acid synthetase system in the plastids from the mesocarp of avocado (Persea americana) fruit | journal = Eur. J. Biochem. | volume = 123 | pages = 553–61 | pmid = 7075600 | issue = 3 }}

3 : EC 1.1.1|NADH-dependent enzymes|Enzymes of unknown structure

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