“4-chlorobenzoyl-CoA dehalogenase”的意思、由来-开放百科全书

词条

4-chlorobenzoyl-CoA dehalogenase

释义

References

{{enzyme
| Name = 4-chlorobenzoyl-CoA dehalogenase
| EC_number = 3.8.1.7
| CAS_number = 141583-18-8
| IUBMB_EC_number = 3/8/1/7
| GO_code = 0018787
| image =
| width =
| caption =
}}

In enzymology, a 4-chlorobenzoyl-CoA dehalogenase ({{EC number|3.8.1.7}}) is an enzyme that catalyzes the chemical reaction

4-chlorobenzoyl-CoA + H₂O 4-hydroxybenzoyl CoA + chloride

Thus, the two substrates of this enzyme are 4-chlorobenzoyl-CoA and H₂O, whereas its two products are 4-hydroxybenzoyl CoA and chloride.

This enzyme belongs to the family of hydrolases, specifically those acting on halide bonds in carbon-halide compounds. The systematic name of this enzyme class is 4-chlorobenzoyl CoA chlorohydrolase. This enzyme participates in 2,4-dichlorobenzoate degradation.

References

{{cite journal | vauthors = Chang KH, Liang PH, Beck W, Scholten JD, Dunaway-Mariano D | date = 1992 | title = Isolation and characterization of the three polypeptide components of 4-chlorobenzoate dehalogenase from Pseudomonas sp. strain CBS-3 | journal = Biochemistry | volume = 31 | pages = 5605–10 | pmid = 1610806 | doi = 10.1021/bi00139a025 | issue = 24 }}
{{cite journal | vauthors = Crooks GP, Copley SD | date = 1994 | title = Purification and characterization of 4-chlorobenzoyl CoA dehalogenase from Arthrobacter sp. strain 4-CB1 | journal = Biochemistry | volume = 33 | pages = 11645–9 | pmid = 7918379 | doi = 10.1021/bi00204a028 | issue = 38 }}

2 : EC 3.8.1|Enzymes of unknown structure

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