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词条 4-hydroxybenzoyl-CoA reductase
释义

  1. Nomenclature

  2. References

  3. Further reading

{{enzyme
| Name = 4-hydroxybenzoyl-CoA reductase
| EC_number = 1.3.7.9
| CAS_number =
| GO_code = 0018525
| image =
| width =
| caption =
}}

In enzymology, a 4-hydroxybenzoyl-CoA reductase ({{EC number|1.3.7.9}}) is an enzyme found in some bacteria and archaea that catalyzes the chemical reaction[1][2]

benzoyl-CoA + acceptor + H2O 4-hydroxybenzoyl-CoA + reduced acceptor

The 3 substrates of this enzyme are benzoyl-CoA, acceptor, and H2O, whereas its two products are 4-hydroxybenzoyl-CoA and reduced acceptor.

This enzyme participates in benzoate degradation via coa ligation.

Nomenclature

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-CH group of donor with other acceptors. The systematic name of this enzyme class is benzoyl-CoA:acceptor oxidoreductase. Other names in common use include:

  • 4-hydroxybenzoyl-CoA reductase (dehydroxylating), and
  • 4-hydroxybenzoyl-CoA:(acceptor) oxidoreductase.

References

1. ^{{cite journal | vauthors = Glockler R, Tschech A, Fuchs G | date = 1989 | title = Reductive dehydroxylation of 4-hydroxybenzoyl-CoA to benzoyl-CoA in a denitrifying, phenol-degrading Pseudomonas species | journal = FEBS Lett. | volume = 251 | pages = 237–40 | pmid = 2753161 | doi = 10.1016/0014-5793(89)81461-9 | issue = 1–2 }}
2. ^{{cite journal | vauthors = Heider J, Boll M, Breese K, Breinig S, Ebenau-Jehle C, Feil U, Gad'on N, Laempe D, Leuthner B, Mohamed ME, Schneider S, Burchhardt G, Fuchs G | title = Differential induction of enzymes involved in anaerobic metabolism of aromatic compounds in the denitrifying bacterium Thauera aromatica | journal = Arch. Microbiol. | volume = 170 | issue = 2 | pages = 120–31 |date=August 1998 | pmid = 9683649 | doi = 10.1007/s002030050623 }}

Further reading

{{refbegin}}
  • {{cite journal | vauthors = Breese K, Fuchs G | date = 1998 | title = 4-Hydroxybenzoyl-CoA reductase (dehydroxylating) from the denitrifying bacterium Thauera aromatica--prosthetic groups, electron donor, and genes of a member of the molybdenum-flavin-iron-sulfur proteins | journal = Eur. J. Biochem. | volume = 251 | pages = 916–23 | pmid = 9490068 | doi = 10.1046/j.1432-1327.1998.2510916.x | issue = 3 }}
  • {{cite journal | vauthors = Brackmann R, Fuchs G | date = 1993 | title = Enzymes of anaerobic metabolism of phenolic compounds 4-Hydroxybenzoyl-CoA reductase (dehydroxylating) from a denitrifying Pseudomonas species | journal = Eur. J. Biochem. | volume = 213 | pages = 563–71 | pmid = 8477729 | doi = 10.1111/j.1432-1033.1993.tb17795.x | issue = 1 }}
  • {{cite journal | vauthors = Heider J, Fuchs G | date = 1997 | title = Anaerobic metabolism of aromatic compounds | journal = Eur. J. Biochem. | volume = 243 | pages = 577–96 | pmid = 9057820 | doi = 10.1111/j.1432-1033.1997.00577.x | issue = 3 }}
{{refend}}{{CH-CH oxidoreductases}}{{Enzymes}}{{Portal bar|Molecular and Cellular Biology|border=no}}{{1.3-enzyme-stub}}

2 : EC 1.3.7|Enzymes of known structure

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