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词条 List of investigational sexual dysfunction drugs
释义

  1. Atrophic vaginitis

  2. Erectile dysfunction

  3. Female anorgasmia

  4. Female sexual dysfunction

  5. Premature ejaculation

  6. Unspecified

  7. See also

  8. References

  9. External links

This is a list of investigational sexual dysfunction drugs, or drugs that are currently under development for clinical treatment of sexual dysfunction but are not yet approved. Chemical/generic names are listed first, with developmental code names, synonyms, and brand names in parentheses.

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Atrophic vaginitis

  • Estetrol (E4; Donesta) – estrogen receptor agonist  
  • Lasofoxifene (CP-336156, CP-336156-CB, Fablyn, Oporia) – selective estrogen receptor modulator 

Erectile dysfunction

  • HCP-1302 – undefined mechanism of action 
  • Nitroglycerin gel (Eroxon, Futura, MED-2001–MED-2005) – nitric oxide donor 
  • Tadalafil/tamsulosin (HCP-1303, CKD-397, YBH-1603)    
  • TT-701 (LY-2452473) – selective androgen receptor modulator 

Female anorgasmia

  • Testosterone low-dose intranasal (MPP-14, TBS-2, Noseafix, Tefina) – androgen receptor agonist  

Female sexual dysfunction

  • BP-101 – undefined mechanism of action  
  • Bremelanotide (PT-141, Rekynda) – non-selective melanocortin receptor agonist  
  • Bupropion/trazodone (S1P-104, S1P-205, Lorexys, Orexa) – norepinephrine reuptake inhibitor, nicotinic acetylcholine receptor antagonist, 5-HT2A receptor antagonist, α1-adrenergic receptor antagonist, weak serotonin reuptake inhibitor 
  • Buspirone/testosterone (Lybridos) – 5-HT1A receptor partial agonist and androgen receptor agonist  
  • Lasofoxifene (CP-336156, CP-336156-CB, Fablyn, Oporia) – selective estrogen receptor modulator  
  • PL-6983 – selective MC4 receptor agonist  
  • Sildenafil/testosterone (Lybrido) – PDE5 inhibitor and androgen receptor agonist  
  • TGFK09SD – 5-HT1A receptor agonist  

Premature ejaculation

  • Clomipramine/sildenafil (CDFR-0812) – serotonin reuptake inhibitor and PDE5 inhibitor  
  • DA-8031 – serotonin reuptake inhibitor  
  • IX-01 – oxytocin receptor antagonist  
  • OnabotulinumtoxinA (botulinum toxin A, Botox) – acetylcholine release inhibitor 
  • Tramadol (BIO-301, DMI-7958, LI-301, LIF-301, Zertane) – μ-opioid receptor agonist, serotonin releasing agent, norepinephrine reuptake inhibitor, and 5-HT2C receptor antagonist  

Unspecified

  • Vilazodone (Viibryd, EMD-68843, SB-659746A) – 5-HT1A receptor partial agonist and serotonin reuptake inhibitor  

See also

  • List of investigational drugs

References

External links

  • AdisInsight - Springer
{{Sexual dysfunction pharmacotherapies}}{{Drugs for erectile dysfunction and premature ejaculation}}

3 : Drug-related lists|Experimental drugs|Sexual dysfunction drugs

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