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词条 L. S. Shashidhara
释义

  1. Biography

  2. Legacy

  3. Awards and honours

  4. Selected bibliography

      Scientific articles    General articles  

  5. See also

  6. Notes

  7. References

  8. External links

{{EngvarB|date=March 2018}}{{Use dmy dates|date=March 2018}}{{Infobox scientist
| name = L. S. Shashidhara
| image = Prof L S Shashidhara.jpg
| alt =
| caption =
| birth_date = {{Birth date and age|df=y|1963|3|23}}
| birth_place = Karnataka, India
| death_date =
| death_place =
| residence = Pune. Maharashtra, India
| nationality = Indian
| fields = {{ublist | Genetics | Developmental biology }}
| workplaces = {{ublist | Centre for Cellular and Molecular Biology | Indian Institutes of Science Education and Research | Jawaharlal Nehru Centre for Advanced Scientific Research }}
| alma_mater = {{ublist | University of Agricultural Sciences, Dharwad | University of Cambridge | National Centre for Biological Sciences }}
| doctoral_advisor =
| doctoral_students =
| known_for = Studies on Drosophila
| awards = {{ublist | 2003 CSIR Technology Prize | 2006 DAE-SRC Outstanding Research Investigator Award | 2008 Shanti Swarup Bhatnagar Prize }}
}}Lingadahalli Subrahmanya Shashidhara (born 1963) is an Indian developmental biologist, geneticist and a professor of Biology at the Indian Institute of Science Education and Research, Pune.[1] He heads the LSS Laboratory at IISER[2] and is known for his studies on Drosophila, particularly Evolution of appendages and functions of homeotic selector genes.[3] He is a J. C. Bose National Fellow of the Department of Science and Technology and an elected fellow of the Indian National Science Academy,[4] Indian Academy of Sciences[5] and the National Academy of Sciences, India.[6] The Council of Scientific and Industrial Research, the apex agency of the Government of India for scientific research, awarded him the Shanti Swarup Bhatnagar Prize for Science and Technology, one of the highest Indian science awards, in 2008, for his contributions to biological sciences.[7]

He is also a member of visiting faculty of Biology at Ashoka University, Sonepat, India.[8]

Biography

L. S. Shashidhara, born on 23 March 1963 in the south Indian state of Karnataka, graduated in science from University of Agricultural Sciences, Dharwad (UAS) in 1985 and obtained a master's degree in Genetics and Plant breeding in 1987 from the same university.[9] After a brief stint (1987–88) at UAS as a teaching associate, he moved to University of Cambridge in 1988 for his doctoral studies to secure a PhD in 1991. On completion of his post-doctoral studies at Cambridge (1991–93), he returned to India to join National Centre for Biological Sciences and worked as a visiting fellow for two years. Subsequently, he moved to Centre for Cellular and Molecular Biology (CCMB) in 1995 as a scientist (group leader)[10] where he served till 2007 when he was transferred, on deputation, to the Pune centre of Indian Institutes of Science Education and Research (IISER) as a professor.[11] Since then, he has been serving the institute as a professor and chair of Biology and is the co-ordinator of the department of Biology.[12] He pursues his research interests as the head of the LSS Laboratory at IISER where he hosts a number doctoral and post-doctoral scholars.[2] He also serves as an honorary professor at Jawaharlal Nehru Centre for Advanced Scientific Research[11] and is the incumbent vice-president of the Indian National Science Academy.[13]

Legacy

Shashidhara's researches were focused on developmental biology, specifically the development of limbs and the role played by Ultrabithorax, a Hox gene, functioning as a transcription factor.[14] Studying Drosophila melanogaster (commonly known as fruit fly) as a model, he elucidated the molecular pathways Wnt, TGF-? and EGFR/Ras that impact the growth control and developed a fly model for studying Adenomatous polyposis coli, the colon cancer gene in humans. His studies are reported to have assisted in a wider understanding of the relation between genes and diseases in humans and in the development of cancer drug discovery systems.[4] His research findings have been published in a number of articles{{Refn|group=note|25 of his articles are reported to be high-impact articles[4]}} published in peer-reviewed journals,[15] several of them have been listed in online article repositories such as Metascience,[16] PubMed,[17] and ResearchGate.[18] He has also published many general articles on adacemics{{Refn|group=note|Please see General articles section}} and has delivered keynote addresses and featured talks.[19][20] He is the secretary-general of the International Union of Biological Sciences (IUBS),[21] and is associated with the Journal of Genetics and Current Science as their associate editor and with Scientific Reports as a member of its editorial board.[11]

Awards and honours

Shashidhara, a J. C. Bose National Fellow of the Department of Science and Technology, received the Technology Prize in Biological Sciences of the Council of Scientific and Industrial Research in 2003[13] and the Outstanding Research Investigator Award of the Science Research Council of the Department of Atomic Energy in 2006.[11] The Indian academy of Sciences elected him as a fellow in 2007 and he became an elected fellow of the Indian National Science Academy[4] and the National Academy of Sciences, India in 2008. The same year he received the Shanti Swarup Bhatnagar Prize of the Council of Scientific and Industrial Research, one of the highest Indian science awards, for his contributions to Biological Sciences.[7]

Selected bibliography

Scientific articles

  • {{cite journal | title=A comparative genomic analysis of targets of Hox protein Ultrabithorax amongst distant insect species | author=Naveen Prasad, Shreeharsha Tarikere, Dhanashree Khanale, Farhat Habib, Lingadahalli S Shashidhara | journal=Scientific Reports | year=June 2016 | volume=6 | page=27885 | doi=10.1038/srep27885 | pmid=27296678 | pmc=4906271}}
  • {{cite book | title=ChIP for Hox Proteins from Drosophila Imaginal Discs | author=Pavan Agrawal, Lingadahalli S Shashidhara | journal=Methods in Molecular Biology | year=August 2013 | volume=1196 | pages=241–253 | doi=10.1007/978-1-4939-1242-1_15| pmid=25151168 | isbn=978-1-4939-1241-4 }}
  • {{cite journal | title=Distinct Transcriptional Networks in Quiescent Myoblasts: A Role for Wnt Signaling in Reversible vs. Irreversible Arrest | author=Sindhu Subramaniam, Prethish Sreenivas, Sirisha Cheedipudi, Vatrapu Rami Reddy, Lingadahalli S Shashidhara, Ravi Kumar Chilukoti, Madhavi Mylavarapu, Jyotsna Dhawan | journal=PLoS ONE | year=June 2013 | volume=8 | issue=6 | doi=10.1371/journal.pone.0065097 | pmid=23755177 | pmc=3670900 | page=e65097}}
  • {{cite journal | title=Drosophila apc regulates delamination of invasive epithelial clusters | author=F M De Graeve, Véronique Van De Bor, C Ghiglione, Stephane Noselli | journal=Developmental Biology | year=May 2012 | volume=368 | issue=1 | pages=76–85 | doi=10.1016/j.ydbio.2012.05.017 | pmid=22627290}}
  • {{cite journal | title=Negative regulation ofUltrabithorax expression byengrailed is required for proper specification of wing development inDrosophila melanogaster | author=Bright Starling Emerald, Lingadahalli S Shashidhara | journal=Journal of Genetics | year=April 2012 | volume=1 | issue=79 | pages=61–70 | doi=10.1007/BF02728947}}
  • {{cite journal | title=Genome-level identification of targets of Hox protein Ultrabithorax in Drosophila: novel mechanisms for target selection | author=Pavan Agrawal, Farhat Habib, Ramesh Yelagandula, L. S. Shashidharaa | journal=Scientific Reports | year=December 2011 | volume=1 | issue=205 | pages=205 | doi=10.1038/srep00205 | pmid=22355720 | pmc=3244697}}
  • {{cite journal | title=The Drosophila Homologue of Ataxin-2 Binding Protein: Toward a Fruit Fly Model of Spinocerebellar Ataxia Type 2? | author=N Usha, LS Shashidhara | journal=Alternatives to Laboratory Animals: ATLA | year=March 2011 | volume=39 | issue=1 | pages=70}}
  • {{cite journal | title=Human APC sequesters β-catenin even in the absence of GSK-3β in a Drosophila model | author=P R Rao, Kalpana Makhijani, Lingadahalli S Shashidhara | journal=Oncogene | year=May 2008 | volume=27 | issue=17 | pages=2488–93 | doi=10.1038/sj.onc.1210890| pmid=17968317 }}

General articles

  • {{cite journal | title=Edward B Lewis (1918–2004) | author=Lingadahalli S Shashidhara | journal=Journal of Genetics | year=August 2004 | volume=83 | issue=2 | pages=219 | doi=10.1007/BF02729900}}
  • {{cite journal | url=https://indiabioscience.org/columns/opinion/what-is-interdisciplinary-science | title=What is interdisciplinary science? | author=L. S. Shashidhara | journal=IndiaBioscience | date=10 July 2011}}
  • {{cite journal | url=https://indiabioscience.org/columns/education/science-education-and-research-in-21st-century-india | title=Science education and research in 21st century India | author=L. S. Shashidhara | journal=IndiaBioscience | date=16 July 2011}}
  • {{cite journal | url=https://indiabioscience.org/columns/opinion/postdoctoral-culture | title=Postdoctoral Culture | author=L. S. Shashidhara | journal=IndiaBioscience | date=3 August 2011}}
  • {{cite journal | url=https://indiabioscience.org/columns/opinion/democracy-in-our-research-organizations | title=Democracy in our research organizations | author=L. S. Shashidhara | journal=IndiaBioscience | date=31 August 2011}}
  • {{cite journal | url=https://indiabioscience.org/columns/indian-scenario/understanding-bureaucracy | title=Understanding bureaucracy | author=L. S. Shashidhara | journal=IndiaBioscience | date=3 December 2011}}
  • {{cite journal | title=Who are 'people of genius'? | author=Lingadahalli S Shashidhara | journal=Current Science | year=September 2014 | volume=107 | issue=5 | pages=731–732}}
  • {{cite journal | url=https://indiabioscience.org/columns/indian-scenario/as-iisers-enter-their-10th-year-a-self-congratulatory-note-on-biology-research | title=As IISERs enter their 10th year, a self-congratulatory note on Biology research | author=L. S. Shashidhara | journal=IndiaBioscience | date=16 December 2015}}

See also

{{Div col|colwidth=30em}}
  • Drosophila melanogaster
  • Homeotic selector gene
  • Adenomatous polyposis coli
  • Ultrabithorax
{{div col end}}{{portal|India|Biology}}

Notes

1. ^{{cite web | url=http://ssbprize.gov.in/content/Detail.aspx?AID=363 | title=Brief Profile of the Awardee | publisher=Shanti Swarup Bhatnagar Prize |year=2016 | accessdate=5 October 2016}}
2. ^{{cite web | url=http://www.iiserpune.ac.in/~ls.shashidhara/ | title=LSS Lab Home | publisher=LSS Lab – IISER |year=2016 | accessdate=26 October 2016}}
3. ^{{cite web | url=http://www.sandhyasekar.com/conf/speaker/l-s-shashidhara/ | title=L S Shashidhara – Biography | work=2016 | publisher=IISER Thiruvananthapuram | accessdate=26 October 2016}}
4. ^{{cite web | url=http://insaindia.res.in/detail.php?id=P07-1446 | title=Indian fellow – Shashidhara | publisher=Indian National Science Academy |year=2016 | accessdate=25 October 2016}}
5. ^{{cite web | url=http://www.ias.ac.in/describe/fellow/Shashidhara,_Prof._Lingadahalli_Subrahmanya | title=Fellow Profile – Shashidhara | publisher=Indian Academy of Sciences |year=2016 | accessdate=25 October 2016}}
6. ^{{cite web | url=http://nasi.nic.in/fellows.asp?RsFilter=S | title=NASI fellows | publisher=National Academy of Sciences, India |year=2016 | accessdate=26 October 2016}}
7. ^{{cite web | url=http://ssbprize.gov.in/Content/AwardeeList.aspx | title=View Bhatnagar Awardees | publisher=Shanti Swarup Bhatnagar Prize |year=2016 | accessdate=5 October 2016}}
8. ^{{Cite web|url=https://www.ashoka.edu.in/stories/welcome-246|title=Prof. L S Shashidhara joins Ashoka University as the Distinguished Visiting Professor of Biology|last=University|first=Ashoka|publisher=Ashoka University|access-date=9 November 2017}}
9. ^{{cite web | url=http://www.ccmb.res.in/staff/shashi/publication.html | title=Brief Biodata | publisher=Centre for Cellular and Molecular Biology |year=2016 | accessdate=26 October 2016}}
10. ^{{cite web | url=http://www.ccmb.res.in/staff/shashi/droso.html | title=Drosophila Genetics & Developmental Biology | publisher=CCMB |year=2016 | accessdate=26 October 2016}}
11. ^{{cite web | url=http://www.iiserpune.ac.in/~ls.shashidhara/lab-members/prof-ls-shashidhara-2.html | title=Prof. LS Shashidhara – LSS Lab | publisher=IISER, PUne |year=2016 | accessdate=26 October 2016}}
12. ^{{cite web | url=https://openi.nlm.nih.gov/detailedresult.php?img=PMC2646550_JCB_200812123_Fig13&req=4 | title=Coordinator – Department of Biology | publisher=Open Access Biomedical Image Search Engine |year=2016 | accessdate=26 October 2016}}
13. ^{{cite web | url=http://www.iiserpune.ac.in/news/prof-ls-shashidhara-elected-vice-president-of-the-indian-national-science-academy | title=Prof. LS Shashidhara elected Vice President of the Indian National Science Academy | publisher=IISER Pune News | date=13 January 2016 | accessdate=26 October 2016}}
14. ^{{cite web | url=http://www.csirhrdg.res.in/ssb.pdf | title=Handbook of Shanti Swarup Bhatnagar Prize Winners | publisher=Council of Scientific and Industrial Research |year=1999 | accessdate=5 October 2016 | pages=34}}
15. ^{{cite web | url=http://repository.ias.ac.in/view/fellows/Shashidhara=3ALingadahalli_Subrahmanya=3A=3A.html | title=Publication by Fellows | work=Article listing | publisher=Indian Academy of Sciences |year=2016 | accessdate=26 October 2016}}
16. ^{{cite web | url=https://meta.science/author/102377886_lingadahalli_subrahmanya_shashidhara | title=Lingadahalli Subrahmanya Shashidhara on Metascience | publisher=Metascience |year=2016 | accessdate=26 October 2016}}
17. ^{{cite web | url=https://www.ncbi.nlm.nih.gov/pubmed/?term=Shashidhara%20LS%5BAuthor%5D&cauthor=true&cauthor_uid=22355720 | title=Shashidhara on PubMed | publisher=PubMed |year=2016 | accessdate=26 October 2016 | author=Author profile}}
18. ^{{cite web | url=https://www.researchgate.net/profile/Lingadahalli_Shashidhara/publications | title=Lingadahalli S Shashidhara on ResearchGate | publisher=ResearchGate |year=2016 | accessdate=26 October 2016}}
19. ^{{cite web | url=http://cscs.res.in/events_folder/talks-and-work-in-progress/cscsevent.2010-02-25.1865742899 | title=Behavioural Adaptations and Evolution | work=Featured talk | publisher=Centre for the Study of Culture and Society | date=11 March 2010 | accessdate=26 October 2016 | author=L. S. Shashidhara}}
20. ^{{cite web | url=http://www.sandhyasekar.com/conf/session/l-s-shashidhara/ | title=Cell Biology of Organ Development in Drosophila | publisher=IISER | date=7 December 2015 | accessdate=26 October 2016}}
21. ^{{cite web | url=https://www.iubs.org/iubs/currentboard.html | title=IUBS Officers and Executive Committee Members | publisher=International Union of Biological Sciences |year=2016 | accessdate=26 October 2016}}

References

{{reflist}}

External links

  • {{cite web | url=http://www.imsc.res.in/~sitabhra/meetings/school10/Shashidhara_Chennai2010_lecture3.pdf | title=Hox genes and evolution of body plan | work=Lecture – full text | publisher=Indian Institute of Science Education and Research |year=2010 | accessdate=26 October 2016 | author=L. S. Shashidhara}}
  • {{cite web | url=https://www.youtube.com/watch?v=0w9jCnCk6Xk | title=NCBS talk 1 | work=Lecture – YouTube video | publisher=TheNCBSnewsteam's channel | date=22 September 2010 | accessdate=26 October 2016 | author=L. S. Shashidhara}}
{{SSBPST recipients in Biological Science}}{{authority control}}{{DEFAULTSORT:Shashidhara, L. S.}}

14 : Recipients of the Shanti Swarup Bhatnagar Award in Biological Science|1963 births|Scientists from Karnataka|Alumni of the University of Cambridge|National Centre for Biological Sciences faculty|Indian Institutes of Science Education and Research|20th-century Indian biologists|Indian geneticists|Indian scientific authors|Fellows of the Indian Academy of Sciences|Fellows of the Indian National Science Academy|Fellows of The National Academy of Sciences, India|Living people|Indian Institute of Science Education and Research, Pune faculty

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