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词条 LTN1
释义

  1. Function

  2. References

  3. Further reading

{{Infobox_gene}}Listerin E3 ubiquitin protein ligase 1 (LTN1), otherwise known as listerin, is a protein that in humans is encoded by the LTN1 gene.[1]

Function

Like most RING finger proteins, listerin functions as an E3 ubiquitin ligase.[2] Listerin is a component of the ribosome quality control complex.[3][4]

References

1. ^{{cite web | title = Entrez Gene: Listerin E3 ubiquitin protein ligase 1 | url = https://www.ncbi.nlm.nih.gov/gene/26046 }}
2. ^{{cite journal | vauthors = Chu J, Hong NA, Masuda CA, Jenkins BV, Nelms KA, Goodnow CC, Glynne RJ, Wu H, Masliah E, Joazeiro CA, Kay SA | title = A mouse forward genetics screen identifies LISTERIN as an E3 ubiquitin ligase involved in neurodegeneration | journal = Proceedings of the National Academy of Sciences of the United States of America | volume = 106 | issue = 7 | pages = 2097–103 | date = February 2009 | pmid = 19196968 | doi = 10.1073/pnas.0812819106 | pmc = 2650114 }}
3. ^{{cite journal | vauthors = Shao S, Brown A, Santhanam B, Hegde RS | title = Structure and assembly pathway of the ribosome quality control complex | journal = Molecular Cell | volume = 57 | issue = 3 | pages = 433–44 | date = February 2015 | pmid = 25578875 | doi = 10.1016/j.molcel.2014.12.015 }}
4. ^{{cite journal | vauthors = Shao S, von der Malsburg K, Hegde RS | title = Listerin-dependent nascent protein ubiquitination relies on ribosome subunit dissociation | journal = Molecular Cell | volume = 50 | issue = 5 | pages = 637–48 | date = June 2013 | pmid = 23685075 | doi = 10.1016/j.molcel.2013.04.015 }}

Further reading

{{refbegin | 2}}
  • {{cite journal | vauthors = Rose JE, Behm FM, Drgon T, Johnson C, Uhl GR | title = Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score | journal = Molecular Medicine | volume = 16 | issue = 7–8 | pages = 247–53 | year = 2010 | pmid = 20379614 | pmc = 2896464 | doi = 10.2119/molmed.2009.00159 }}
  • {{cite journal | vauthors = Shao S, Brown A, Santhanam B, Hegde RS | title = Structure and assembly pathway of the ribosome quality control complex | journal = Molecular Cell | volume = 57 | issue = 3 | pages = 433–44 | date = February 2015 | pmid = 25578875 | pmc = 4321881 | doi = 10.1016/j.molcel.2014.12.015 }}
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