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词条 LysM RNA motifs
释义

  1. References

{{DISPLAYTITLE:lysM RNA motifs}}lysM RNA motifs are conserved RNA structures that were discovered by bioinformatics.[1]

Such bacterial motifs are defined by consistently being upstream of 'lysM' genes, which encode lysin protein domains, a conserved domain that participates in cell wall degradation.

lysM motif RNAs likely function as cis-regulatory elements, in view of their positions upstream of protein-coding genes, although this hypothesis is not certain.

Three lysM RNA motifs have been found. lysM-Actino motif RNAs are found in Actinomycetales.

lysM-Prevotella motif RNAs are found in the genus Prevotella.

The lysM-TM7 RNA motif occurs only in the poorly understood phylum TM7.

A part of the lysM-Actino motif is likely the Shine-Dalgarno sequence of the downstream lysM gene. Thus, these RNAs might regulate the downstream gene translationally.

References

1. ^{{cite journal |vauthors=Weinberg Z, Lünse CE, Corbino KA, Ames TD, Nelson JW, Roth A, Perkins KR, Sherlock ME, Breaker RR |title=Detection of 224 candidate structured RNAs by comparative analysis of specific subsets of intergenic regions |journal=Nucleic Acids Res. |volume=45 |issue=18 |pages=10811-10823 |date=October 2017 |pmid=28977401 |pmc=5737381 |doi=10.1093/nar/gkx699 |url=}}
{{Navbox
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| title = Gallery of LysM RNA motifs
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| lines=5
| Image:RF03090.svg|lysM-Actino Secondary structure taken from the Rfam database. Family RF03090
| Image:RF03002.svg|lysM-Prevotella Secondary structure taken from the Rfam database. Family RF03002
| Image:RF03005.svg|lysM-TM7 Secondary structure taken from the Rfam database. Family RF03005
}}
}}

1 : Non-coding RNA

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