| 词条 | M23 RNA motif |
| 释义 |
| Name = M23 | image = RF03006.svg | width = | caption = Consensus secondary structure and sequence conservation of M23 RNA | Symbol = M23 | AltSymbols = | Rfam = RF03006 | miRBase = | miRBase_family = | RNA_type = Gene; sRNA | Tax_domain = | GO = | SO = {{SO|0001263}} | CAS_number = | EntrezGene = | HGNCid = | OMIM = | RefSeq = | Chromosome = | Arm = | Band = | LocusSupplementaryData = }} The M23 RNA motif is a conserved RNA structure that was discovered by bioinformatics.[1] M23 motif RNAs are found in Clostridia. M23 RNAs are generally located upstream of protein-coding genes, and therefore they might function as cis-regulatory elements. Most M23 RNAs are located upstream of M23 peptidase genes, but one is upstream of a gene whose product is NAD synthetase. However, there were two cases where no downstream gene was located.[1] While these cases had technical explanations not related to biology,[1] it is possible they the technical explanations do not apply, and that the M23 RNA motif functions as a small RNA. An M23 RNA was observed to apparently bind a molecule in yeast extract.[1] However, this putative molecule has not (as of 2018) been identified. References1. ^1 2 3 {{cite journal |vauthors=Weinberg Z, Lünse CE, Corbino KA, Ames TD, Nelson JW, Roth A, Perkins KR, Sherlock ME, Breaker RR |title=Detection of 224 candidate structured RNAs by comparative analysis of specific subsets of intergenic regions |journal=Nucleic Acids Res. |volume=45 |issue=18 |pages=10811-10823 |date=October 2017 |pmid=28977401 |pmc=5737381 |doi=10.1093/nar/gkx699 |url=}} 1 : Non-coding RNA |
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