词条 | Marcey Waters |
释义 |
| name = Marcey L. Waters | fields = Chemical Biology | alma_mater = UCSD, University of Chicago | doctoral_advisor = William Wulff | known_for = Bioorganic Chemistry, Molecular Recognition, Supramolecular Chemistry, Peptide Chemistry, Nuclear Magnetic Resonance, Peptidomimetics, and Combinatorial Chemistry }} Marcey Lynn Waters is a chemical biologist and Vice Chair for Education at the University of North Carolina, Chapel Hill. She studies peptide folding and supramolecular systems of biomolecules. Waters has received multiple awards, distinguished professorships, fellowships, and serves as the 2018 President of the American Peptide Society. EducationWaters graduated from the University of California, San Diego with a degree in chemistry. While an undergraduate, she worked with Prof. Charles L. Perrin[1] on 1H NMR spectroscopy of organic molecules. Waters entered the University of Chicago for her doctoral degree in chemistry, working with Prof. William D. Wulff on the physical chemistry of organometallic alkyne systems, yielding Fischer carbene complexes.[2] The mechanism for the Wulff-Dotz benzannulation reaction is still under discussion. ResearchWaters joined UNC-Chapel Hill as an assistant professor in 1999. As of 2018, she was the Gordon and Bowman Gray Distinguished term professor and Glen H. Elder Distinguished professor.[3] Waters' research began with studies of non-covalent organizing interactions in peptide beta-hairpin turn backbone model systems, specifically, how pi-pi and cation-pi system interactions could influence peptide organization.[4][5] This research can also extend to molecular recognition,[6] in which specific peptide cavities can be designed to "host" selected organic molecules. Waters' group also studies protein and peptide methylation patterns and their biophysical interactions, which can relate to epigenetic disease mechanisms.[7] She collaborated with faculty colleague Nancy Albritton to study degrons of proteolytically cleaved ubiquitins.{{fact|date=October 2018}} Volunteer serviceMentorshipWaters was involved in mentorship of chemistry students from nontraditional and disadvantaged backgrounds as part of the American Chemical Society's Project SEED.[8] She has advanced multiple campus groups encouraging women scholars in physical sciences.[9] Waters mentored for TANDEMplusIDEA, the international mentoring program for female scientists from 2007 to 2009. Waters was on the Board of Directors for the Mesilla Chemistry Workshop held in July from 2006 to 2018. From 2011 to 2013, Waters was a UNC WOWS Scholar (Working on Women in Science). From 2013 to 2018, she was a Faculty Advisor for UNC WISE (Women in Science and Engineering, graduate student organization). Journal and conference boardsIn 2007, Waters served as Co-chair for the International Symposium on Dynamic Combinatorial Chemistry (November). The year after that, she was an Advisory Board Member of International Symposia on Macrocyclic and Supramolecular Chemistry (ISMSC). In 2009, she was a guest editor for the December issue of Current Opinion in Chemical Biology. From 2009 to 2015, she was an Advisory Board Member of International Symposia on Macrocyclic and Supramolecular Chemistry (ISMSC). In 2011, Waters was a Co-Organizer of the Mesilla Chemistry Workshop on “Aromatic Interactions in Chemistry and Biology”(with Ken Houk, UCLA Dept of Chemistry). In 2012, Waters was a Section Editor for “Supramolecular Chemistry: From Molecules to Nanomaterials” (John Wiley and Sons). In 2013, she was the Co-Chair, of American Peptide Society Meeting (with David Lawrence, UNC Dept of Chemistry) and a guest editor for Accounts of Chemical Research for the “Aromatic Interactions in Chemistry and Biology” article in the April Issue. From 2014 to 2020, Waters was an Editorial Advisory Board Member of the Journal of the American Chemical Society. Awards and honors
References1. ^{{Cite web|url=https://www.alumni.ucsd.edu/s/1170/index.aspx?sid=1170&gid=1&sitebuilder=1&pgid=4288&content_id=6379|title=Charles Perrin Symposium|website=www.alumni.ucsd.edu|access-date=2018-10-28}} {{Authority control}}{{DEFAULTSORT:Waters, Marcey}}2. ^{{cite journal |last1=Waters |first1=Marcey L. |last2=Bos |first2=Mary E. |last3=Wulff |first3=William |title=Mechanistic Studies on the Reaction of Fischer Carbene Complex with Alkynes: Does the Alkyne Insertion Intermediate Form Irreversibly? |journal=Journal of the American Chemical Society |date=July 1999 |volume=121 |issue=27 |pages=6403–6413 |doi=10.1021/ja983101u }} 3. ^{{Cite news|url=https://chem.unc.edu/faculty/waters-marcey/|title=Waters, Marcey - Department of Chemistry|work=Department of Chemistry|access-date=2018-10-28|language=en-US}} 4. ^{{Cite web|url=https://www.nsf.gov/awardsearch/showAward?AWD_ID=0094068|title=NSF Award Search: Award#0094068 - CAREER: Studies of Pi-Pi Stacking Interactions in Small Molecules and Beta-Turn Peptides|website=www.nsf.gov|access-date=2018-10-28}} 5. ^{{cite journal |last1=Tatko |first1=Chad D. |last2=Waters |first2=Marcey L. |title=Selective Aromatic Interactions in β-Hairpin Peptides |journal=Journal of the American Chemical Society |date=August 2002 |volume=124 |issue=32 |pages=9372–9373 |doi=10.1021/ja0262481 }} 6. ^1 {{Cite web|url=http://www.americanpeptidesociety.org/pages/bio.asp?id=72|title=Marcey Waters|website=www.americanpeptidesociety.org|access-date=2018-10-28}} 7. ^{{Cite news|url=https://chem.unc.edu/research_item/waters-aaas-fellow/|title=Waters AAAS Fellow - Department of Chemistry|work=Department of Chemistry|access-date=2018-10-28|language=en-US}} 8. ^{{Cite web|url=https://pubs.acs.org/cen/acsnews/84/8412acsnews2.html|title=Chemical & Engineering News: ACS News-2005-06 Project SEED College Scholarships|last=News|first=Chemical & Engineering|website=pubs.acs.org|language=en|access-date=2018-10-28}} 9. ^1 2 {{Cite news|url=https://college.unc.edu/2015/06/waters/|title=Waters receives 2015 Mary Turner Lane award - College of Arts & Sciences|date=2015-06-05|work=College of Arts & Sciences|access-date=2018-10-28|language=en-US}} 10. ^{{Cite news|url=https://college.unc.edu/2018/03/uaaw-2018/|title=Spotlight shines on Advancement of Women Award winners|date=2018-03-09|work=College of Arts & Sciences|access-date=2018-12-01|language=en-US}} 11 : Living people|21st-century American chemists|University of North Carolina at Chapel Hill faculty|University of California, San Diego alumni|University of Chicago alumni|American women chemists|Year of birth missing (living people)|21st-century women scientists|Fellows of the American Association for the Advancement of Science|Sloan Research Fellows|Women in science and technology |
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