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词条 Mark H. Schoenfisch
释义

  1. Early life and education

  2. Career

  3. Research

  4. Awards and honors

  5. Commercialization interests

  6. References

  7. External links

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| residence = Chapel Hill, North Carolina
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| fields = Chemistry
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University of Arizona {{small|(Ph.D., 1997)}}}}
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| doctoral_advisor = Jeanne E. Pemberton
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}}Mark H. Schoenfisch ({{IPAc-en|ˈ|ʃ|eɪ|n|f|ɪ|ʃ}} {{respell|SHANE|FISH}}) is an American Analytical Chemist. He is Distinguished Endowed Professor of Chemistry at the University of North Carolina at Chapel Hill and is jointly appointed with the institution's Schools of Medicine and Pharmacy.[1] His research interests include analytical sensors, biomaterials, and the development of macromolecular nitric oxide release scaffolds as novel therapeutics. Intellectual property originating from his research group is the basis of technology being commercialized by Novan, Clinical Sensors, and Novoclem Therapeutics located in the Research Triangle Park.[2]

Early life and education

Mark H. Schoenfisch was born in Elgin, Illinois. He attended William Fremd High school in Palatine, Illinois and graduated from the University of Kansas in 1992 with a B.A. in Chemistry and Germanic Languages & Literature. Schoenfisch went on to receive his Ph.D. in Chemistry at the University of Arizona in 1997.

Career

In 1998, Schoenfisch worked as a NIH Postdoctoral Fellow under the Department of Chemistry at the University of Michigan. He moved to the Chapel Hill, North Carolina, to work as an assistant professor of chemistry at the University of North Carolina at Chapel Hill in 2000, and then as an associate professor of chemistry in 2005. Schoenfisch currently serves as a professor of chemistry as well as an adjunct professor of biomedical engineering at the University of North Carolina at Chapel Hill.

Research

The Schoenfisch group works at the interface analytical chemistry, materials science, biomedical engineering, and biology. Research within the Schoenfisch group is currently focused on four main areas:[2]

  1. Designing macromolecular nitric oxide release vehicles as novel therapeutics for a variety of diseases&91;3&93;
  2. Improving the analytical performance of implantable continuous glucose monitoring devices for diabetes management&91;4&93;
  3. Designing microfluidic nitric oxide (NO) sensors for real-time detection of NO in biological media&91;5&93;
  4. Developing superhydrophobic interfaces for mold prevention and remediation

Awards and honors

In 1998, Schoenfisch received the National Institutes of Health Postdoctoral Fellowship.[6] He received the Society for Analytical Chemists of Pittsburgh Young Investigator Award in 2001, the Eli Lilly and Company Young Investigator Award in 2002, the National Science Foundation CAREER Award in 2004 and the International Union of Pure and Applied Chemistry Young Observer Award in 2005.[1][7][8] Schoenfisch was recognized as a prominent professor in 2007 when he received the John L. Sanders Award for Distinguished Undergraduate Teaching and Service.[9] In 2015, he received both the Chapman Family Teaching Award for Distinguished Teaching of Undergraduates as well as the Institute for the Arts and Humanities Faculty Fellowship.[10][11] In 2018, he received UNC's Office of Commercialization and Economic Development Inventor of the Year Award.[12]

Commercialization interests

Schoenfisch is a co-founder of Novan, Inc. in 2006. The public pharmaceutical company focuses primarily on the development of nitric oxide release-based therapies for dermatological indications. The lead product is an anti-acne drug, which has completed Phase 3 clinical trial.[13] At least two other drugs are being developed, including a topical anti-viral for the treatment of external genital warts caused by the human papillomavirus (HPV), and a topical for the treatment of onychomycosis.[14]

Schoenfisch is also the founder of Clinical Sensors, Inc., 2009. The company focuses on the development of analytical sensors for diabetes and assessment of critically ill patients.[15] The company was selected as 1 of 5 NC IDEA grant recipients (of 175 companies) for seed funding in Dec. 2011. Out of 60 companies, Clinical Sensors, Inc. was the runner-up in the Carolina Challenge.[16] To date, the company has raised $4 million in non-dilutive funding.

References

1. ^{{Cite web|url=http://www.chem.unc.edu/people/faculty/schoenfisch/|title=Department of Chemistry Mark Schoenfisch|last=sahl@email.unc.edu|first=Chemistry Webmaster,|website=www.chem.unc.edu|access-date=2018-03-20}}
2. ^{{Cite web|url=https://www.schoenfischlab.com/|title=Schoenfisch Lab|website=Schoenfisch Lab|access-date=2018-03-20}}
3. ^{{Cite news|url=https://cysticfibrosisnewstoday.com/2018/01/10/novoclem-announces-patent-for-cystic-fibrosis-bacterial-infections-treatment-bioc51/|title=Potential CF Therapy for Bacterial Infections Gets Patent, May Start Clinical Testing|date=2018-01-10|work=Cystic Fibrosis News Today|access-date=2018-04-27}}
4. ^{{Cite news|url=https://www.healthline.com/health-news/tiny-implantable-sensor-able-to-wirelessly-transmit-data-about-your-health#1|title=Health Data Transmitted by Tiny Wireless Sensor|work=Healthline|access-date=2018-04-27}}
5. ^{{Cite news|url=https://www.xconomy.com/raleigh-durham/2017/04/21/biotech-startups-at-unc-showcase-target-urgent-medical-needs/|title=Xconomy: Biotech Startups at UNC Showcase Target Urgent Medical Needs|date=2017-04-21|work=Xconomy|access-date=2018-04-27}}
6. ^{{Cite journal|last=Coneski|first=Peter N.|last2=Schoenfisch|first2=Mark H.|date=2012-05-21|title=Nitric Oxide Release Part III. Measurement and Reporting |journal=Chemical Society Reviews|volume=41|issue=10|pages=3753–3758|doi=10.1039/c2cs15271a |pmc=3341472|pmid=22362308}}
7. ^{{Cite web|url=https://www.nsf.gov/awardsearch/showAward?AWD_ID=0349091|title=NSF Award Search: Award#0349091 - CAREER: Molecular Imaging of Protein Adsorption with Immunoassay-Atomic Force Microscopy|website=www.nsf.gov|access-date=2018-04-27}}
8. ^{{Cite web|url=http://old.iupac.org/news/archives/2005/43rd_council/Agenda_Book05-5.pdf|title=43rd IUPAC Meeting Agenda Book|last=|first=|date=|website=|archive-url=|archive-date=|dead-url=|access-date=}}
9. ^{{Cite web|url=https://alumni.unc.edu/news/22-across-campus-recognized-with-teaching-awards/|title=22 Across Campus Recognized With Teaching Awards - UNC General Alumni Association|website=alumni.unc.edu|access-date=2018-04-27}}
10. ^{{Cite news|url=https://provost.unc.edu/posts/2018/02/02/previous-winners-chapman-family-teaching-awards/|title=Previous Winners of the Chapman Family Teaching Awards - Executive Vice Chancellor & Provost - UNC Chapel Hill|date=2018-02-02|work=Executive Vice Chancellor & Provost - UNC Chapel Hill|access-date=2018-04-27}}
11. ^{{Cite news|url=https://iah.unc.edu/welcome-2015-2016-faculty-fellows/|title=IAH Welcomes 2015–2016 Cohort of Faculty Fellows – INSTITUTE for the ARTS & HUMANITIES|date=2015-08-12|work=INSTITUTE for the ARTS & HUMANITIES|access-date=2018-04-27}}
12. ^{{Cite web|url=https://oced.unc.edu/carolina-innovations-seminar/|title=Carolina Innovations Seminar {{!}} Office of Commercialization and Economic Development|website=oced.unc.edu|access-date=2018-04-27}}
13. ^{{Cite web|url=http://www.novan.com/investors-media/press-releases/novan-announces-positive-phase-2-results-novel-acne-treatmen/|title=Novan Therapeutics :: Novan Announces Positive Phase 2 Results for Novel Acne Treatment|website=www.novan.comaccess-date=2018-04-24}}
14. ^{{Cite web|url=http://www.novan.com/pipeline/sb208/|title=Novan - SB208|website=www.novan.com|access-date=2018-04-24}}
15. ^{{Cite web|url=http://www.clinicalsensors.com/|title=Home|website=Clinical Sensors, Inc.|access-date=2018-04-24}}
16. ^{{Cite web|url=https://www.ncbiotech.org/news/clinical-sensors-awarded-over-15m-nih-grants-advance-nitric-oxide-diagnostic-sepsis|title=Clinical Sensors Awarded Over $1.5M in NIH Grants to Advance Nitric Oxide Diagnostic for Sepsis {{!}} North Carolina Biotechnology Center|website=www.ncbiotech.org|access-date=2018-04-24}}

External links

  • [https://www.schoenfischlab.com/ Schoenfisch Lab]
  • Mark Schoenfisch at UNC
  • [https://scholar.google.com/citations?user=hVZyJw4AAAAJ&hl=en Mark Schoenfisch Publications and Citations]
  • Novan
  • Clinical Sensors
  • Vast Therapeutics
{{authority control}}{{DEFAULTSORT:Schoenfisch, Mark H.}}

6 : Analytical chemists|21st-century American chemists|People from Elgin, Illinois|University of Kansas alumni|University of Arizona alumni|University of North Carolina at Chapel Hill faculty

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