| 词条 | Accelerated phase chronic myelogenous leukemia |
| 释义 |
| name = Aman vibhore | synonyms = | image = | caption = | pronounce = | field = Hematology and oncology | symptoms = | complications = | onset = | duration = | types = | causes = | risks = | diagnosis = | differential = | prevention = | treatment = | medication = | prognosis = | frequency = | deaths = }} Accelerated phase chronic myelogenous leukemia is a phase of chronic myelogenous leukemia in which the disease is progressing.[1] In this phase, 10 to 19 % of the cells in the blood and bone marrow are blast cells (immature blood cells). In the accelerated phase, these leukemia cells grow quickly.{{citation needed|date=June 2018}} SymptomsCommon symptoms include fever, bone pain, and swollen spleen.[2] TreatmentPatients treated with imatinib, dasatinib, and nilotinib have shown meaningful rates of hematologic and cytogenetic response.[3] PrognosisPrognosis is very poor once chronic myelogenous leukemia reaches the accelerated phase; it behaves similarly to acute myeloid leukemia. References1. ^{{Cite journal | author = Moshe Talpaz| year = 2002 | url = http://bloodjournal.hematologylibrary.org/content/99/6/1928.short| title = Imatinib induces durable hematologic and cytogenetic responses in patients with accelerated phase chronic myeloid leukemia: results of a phase 2 study| journal = Blood| volume = 99 | pages =1928–1937 | issue = 6 | doi=10.1182/blood.v99.6.1928}} 2. ^{{cite web|url= https://www.nlm.nih.gov/medlineplus/ency/article/000570.htm |title= Chronic myelogenous leukemia (CML) }} 3. ^{{cite journal|last1=Shah|first1=NP|title=Advanced CML: therapeutic options for patients in accelerated and blast phases.|journal=Journal of the National Comprehensive Cancer Network : JNCCN|date=Mar 2008|volume=6 Suppl 2|pages=S31-S36|pmid=18397679}} External links{{Medical resources| DiseasesDB = | ICD10 = | ICD9 = | ICDO = | OMIM = | MedlinePlus = | eMedicineSubj = | eMedicineTopic = | MeshID = D015465 }}
1 : Chronic myeloid leukemia |
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