词条 | Meclorisone |
释义 |
| Verifiedfields = | Watchedfields = | verifiedrevid = | IUPAC_name = (8S,9R,10S,11S,13S,14S,16R,17R)-9,11-Dichloro-17-hydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one | image = Meclorisone.svg | width = | tradename = | pregnancy_AU = | pregnancy_US = | pregnancy_category = | legal_AU = | legal_CA = | legal_UK = | legal_US = | legal_status = | routes_of_administration = | bioavailability = | protein_bound = | metabolism = | elimination_half-life = | excretion = | CAS_number_Ref = | CAS_number = 4732-48-3 | CAS_supplemental = | class = Corticosteroid; Glucocorticoid | ATC_prefix = | ATC_suffix = | ATC_supplemental = | PubChem = 260706 | IUPHAR_ligand = | DrugBank_Ref = | DrugBank = | ChemSpiderID_Ref = | ChemSpiderID = 228830 | UNII = K18P43Q80N | KEGG = | ChEBI = | ChEMBL = | C=22 | H=28 | Cl=2 | O=4 | SMILES = C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@@]4([C@]3([C@H](C[C@@]2([C@]1(C(=O)CO)O)C)Cl)Cl)C | StdInChI_Ref = | StdInChI = 1S/C22H28Cl2O4/c1-12-8-16-15-5-4-13-9-14(26)6-7-19(13,2)21(15,24)17(23)10-20(16,3)22(12,28)18(27)11-25/h6-7,9,12,15-17,25,28H,4-5,8,10-11H2,1-3H3/t12-,15+,16+,17+,19+,20+,21+,22+/m1/s1 | StdInChIKey_Ref = | StdInChIKey = OKWSMPYQIYKVDC-CXSFZGCWSA-N | synonyms = NSC-92353; 16α-Methyldichlorisone; 9α,11β-Dichloro-17α,21-dihydroxy-16α-methylpregna-1,4-diene-3,20-dione }}Meclorisone (developmental code name NSC-92353) is a synthetic glucocorticoid corticosteroid which was never marketed.[1] References1. ^{{cite book|author=J. Elks|title=The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies|url=https://books.google.com/books?id=0vXTBwAAQBAJ&pg=PA758|date=14 November 2014|publisher=Springer|isbn=978-1-4757-2085-3|pages=758–}} {{Glucocorticoid receptor modulators}}{{steroid-stub}} 6 : Chloroarenes|Diketones|Diols|Glucocorticoids|Pregnanes|Abandoned drugs |
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