“Metallochaperones”的意思、由来-开放百科全书

词条

Metallochaperones

释义

References

Metallochaperones are a distinct class of molecular chaperone that facilitate intracellular transport of metal ions to metalloenzymes and metalloproteins in cells through protein-protein interactions.^[1] The proteins ensure that the correct metal ion is acquired by its corresponding metalloenzyme. Metallochaperones are essential to the proper functioning of cells, playing a vital role in a large number of biological processes including respiration, photosynthesis, neurotransmission.^[2]

Prior to the discovery of metallochaperones in the late 1990s, biologists believed that metal ions freely diffused within cells without the aid of auxiliary proteins.

References

1. ^{{Cite journal|last=Rosenzweig|first=Amy C|date=2002-06-01|title=Metallochaperones: Bind and Deliver|url=http://www.sciencedirect.com/science/article/pii/S1074552102001564|journal=Chemistry & Biology|volume=9|issue=6|pages=673–677|doi=10.1016/S1074-5521(02)00156-4|issn=1074-5521}}
2. ^{{Cite web|url=http://www.eurekaselect.com/93873/article|title=Metallochaperones - an Overview|last=Sekhon|first=Bhupinder Singh|date=2010-05-01|website=Current Chemical Biology|language=en|access-date=2019-01-21}}

4 : Transport proteins|Protein stubs|Biochemistry stubs|Metalloproteins

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