MRSL may refer to:

• Minnesota Recreational Soccer League, an adult soccer association, part of the Minnesota Amateur Soccer League
• Salama Airport, in Costa Rica by ICAO code

• Seremban District
• Seremban Forest Heights
• Seremban Municipal Council
• Seremban-Port Dickson Highway
• Seremban - Port Dickson Highway
• Seremban State Mosque
• Seremban station
• Serempuy
• Seremuk River
• Serena Aunon
• Serena Autieri
• Serena Auñón
• Serena Auñón-Chancellor
• Serena "Bunny" Tsukino
• Serenac
• Serenace
• Serena (character)
• Serena Dalrymple
• Serena Daolio
• Serenade (ballet)
• Serenade Chamber Orchestra
• Serenade Cove
• Serenade (Elgar)
• Serenade for string orchestra, Op.20 (Elgar)
• Serenade for Strings