| 词条 | Myogel |
| 释义 |
Myogel is a human-based extracellular matrix used mainly in the cancer research field to provide 3D cell culture environment for cancer cells. Unlike Matrigel, originated from mice sarcoma, and other synthesized matrices, myogel is extracted from human benign tumor tissue “leiomyoma”. Myogel was developed in Professor Tuula Salo's lab at the University of Oulu/Finland. The idea started by culturing cancer cells on myoma discs (Nurmenniemi et al., 2009). Later on, these myoma tissues were processed (following Matrigel receipt) to extract a gel form called Myogel (Salo et al., 2015). Myogel was compared with Matrigel and found to be superior in term of enhancing cancer cells proliferation, migration and invasion (Salo et al., 2015). References
2 : Extracellular matrix|Cancer research |
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