| 词条 | Nandrolone cyclotate |
| 释义 |
| Verifiedfields = | Watchedfields = | verifiedrevid = | IUPAC_name = [(8R,9S,10R,13S,14S,17S)-13-methyl-3-oxo-2,6,7,8,9,10,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl] 1-methylbicyclo[2.2.2]oct-2-ene-4-carboxylate | image = Nandrolone cyclotate.svg | width = 250px | tradename = | pregnancy_AU = | pregnancy_US = | pregnancy_category = | legal_AU = | legal_CA = | legal_UK = | legal_US = | legal_status = | routes_of_administration = Intramuscular injection | class = Androgen; Anabolic steroid; Androgen ester; Progestogen | bioavailability = | protein_bound = | metabolism = | elimination_half-life = | excretion = | CAS_number_Ref = | CAS_number = 22263-51-0 | CAS_supplemental = | ATC_prefix = | ATC_suffix = | PubChem = 164526 | DrugBank_Ref = | DrugBank = | ChemSpiderID = 32700233 | UNII = 1MG9GW4ZH8 | synonyms = Nandrolone ciclotate; RS-3268R; 19-Nortestosterone 17β-ciclotate | C=28 | H=38 | O=3 | SMILES = C[C@@]12C=C[C@@](CC1)(CC2)C(=O)O[C@@H]3[C@@]4([C@H]([C@H]5[C@@H]([C@@H]6C(=CC(=O)CC6)CC5)CC4)CC3)C | StdInChI_Ref = | StdInChI = 1S/C28H38O3/c1-26-11-14-28(15-12-26,16-13-26)25(30)31-24-8-7-23-22-5-3-18-17-19(29)4-6-20(18)21(22)9-10-27(23,24)2/h11,14,17,20-24H,3-10,12-13,15-16H2,1-2H3/t20-,21+,22+,23-,24-,26-,27-,28-/m0/s1 | StdInChIKey_Ref = | StdInChIKey = REACBNMPQDINOF-ZDMPKJLCSA-N }}Nandrolone cyclotate ({{abbrlink|USAN|United States Adopted Name}}) (developmental code name RS-3268R), or nandrolone ciclotate, also known as 19-nortestosterone 17β-ciclotate, is a synthetic and injected anabolic–androgenic steroid (AAS) of the nandrolone (19-nortestosterone) group which was never marketed.[1][2][3][4] It is an androgen ester – specifically, the C17β ciclotate (4-methylbicyclo[2.2.2]oct-2-ene-1-carboxylate) ester of nandrolone.[1][2] Nandrolone cyclotate has potent and prolonged activity as an AAS when administered by intramuscular injection and is reported to have a similar duration of action to that of nandrolone decanoate via this route.[4]{{Relative affinities of nandrolone and related steroids}} See also
References1. ^1 {{cite book|author=J. Elks|title=The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies|url=https://books.google.com/books?id=0vXTBwAAQBAJ&pg=PA660|date=14 November 2014|publisher=Springer|isbn=978-1-4757-2085-3|pages=660–}} {{Androgen receptor modulators}}{{Progesterone receptor modulators}}{{Genito-urinary-drug-stub}}{{Gastrointestinal-drug-stub}}{{Steroid-stub}}2. ^1 {{cite book|title=Index Nominum 2000: International Drug Directory|url=https://books.google.com/books?id=5GpcTQD_L2oC&pg=PA716|date=January 2000|publisher=Taylor & Francis|isbn=978-3-88763-075-1|pages=716–717}} 3. ^{{cite book|author1=I.K. Morton|author2=Judith M. Hall|title=Concise Dictionary of Pharmacological Agents: Properties and Synonyms|url=https://books.google.com/books?id=tsjrCAAAQBAJ&pg=PA189|date=6 December 2012|publisher=Springer Science & Business Media|isbn=978-94-011-4439-1}} 4. ^1 {{cite journal|last1=van Wayjen|first1=R. G. A.|last2=van den Ende|first2=A.|title=CLINICAL-PHARMACOLOGICAL INVESTIGATION OF THE NITROGEN-RETAINING EFFECT OF NANDROLONE CYCLOTATE|journal=European Journal of Endocrinology|volume=73|issue=1|year=1973|pages=171–178|issn=0804-4643|doi=10.1530/acta.0.0730171}} 5 : Abandoned drugs|Androgens and anabolic steroids|Estranes|Nandrolone esters|Progestogens |
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