| 词条 | Nicocortonide |
| 释义 |
| Verifiedfields = | Watchedfields = | verifiedrevid = | IUPAC_name = 2(1R,2R,10R,11S,12S,14S,15R)-12-Hydroxy-10,14-dimethyl-7-oxo-17-[(1Z)-1-propen-1-yl]-16,18-dioxapentacyclo[13.3.2.01,14.02,11.05,10]icos-5-en-15-yl2-oxoethyl isonicotinate | image = Nicocortonide.svg | width = | tradename = | pregnancy_AU = | pregnancy_US = | pregnancy_category = | legal_AU = | legal_CA = | legal_UK = | legal_US = | legal_status = | routes_of_administration = | bioavailability = | protein_bound = | metabolism = | elimination_half-life = | excretion = | CAS_number_Ref = | CAS_number = 65415-41-0 | CAS_supplemental = | class = Corticosteroid; Glucocorticoid | ATC_prefix = | ATC_suffix = | ATC_supplemental = | PubChem = 70687284 | IUPHAR_ligand = | DrugBank_Ref = | DrugBank = | ChemSpiderID_Ref = | ChemSpiderID = 4940815 | UNII = | KEGG = | ChEBI = | ChEMBL = 2106447 | C=31 | H=37 | N=1 | O=7 | SMILES = C/C=C/C1O[C@@]23CC[C@]([C@]2(C[C@@H]([C@H]4[C@H]3CCC5=CC(=O)CC[C@]45C)O)C)(O1)C(=O)COC(=O)C6=CN=CC=C6 | StdInChI_Ref = | StdInChI = 1S/C31H37NO7/c1-4-6-25-38-30-12-13-31(39-25,24(35)18-37-27(36)19-7-5-14-32-17-19)29(30,3)16-23(34)26-22(30)9-8-20-15-21(33)10-11-28(20,26)2/h4-7,14-15,17,22-23,25-26,34H,8-13,16,18H2,1-3H3/b6-4+/t22-,23+,25?,26-,28+,29+,30-,31+/m1/s1 | StdInChIKey_Ref = | StdInChIKey = NAXHODQTSUXYNT-VOHINOEZSA-N | synonyms = 11β,14α,17α,21-Tetrahydroxypregn-4-ene-3,20-dione cyclic 14,17-acetal with crotonaldehyde, 21-isonicotinate; 11β,21-Dihydroxy-14α,17α-(1-propenylmethylendioxy)pregn-4-ene-3,20-dione 21-isonicotinate }}Nicocortonide is a synthetic glucocorticoid corticosteroid which was never marketed.[1] See also
References1. ^{{cite book|author=J. Elks|title=The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies|url=https://books.google.com/books?id=0vXTBwAAQBAJ&pg=PA865|date=14 November 2014|publisher=Springer|isbn=978-1-4757-2085-3|pages=865–}} {{Glucocorticoid receptor modulators}}{{steroid-stub}} 10 : Alcohols|Corticosteroid cyclic ketals|Corticosteroid esters|Corticosteroids|Cyclic acetals with aldehydes|Esters|Glucocorticoids|Isonicotinates|Pregnanes|Abandoned drugs |
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