词条 | Norclostebol acetate |
释义 |
| Verifiedfields = | Watchedfields = | verifiedrevid = | IUPAC_name = [(8R,9S,10R,13S,14S)-4-Chloro-13-methyl-3-oxo-2,6,7,8,9,10,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl] acetate | image = Norclostebol acetate.svg | width = 250 | tradename = Anabol 4-19 | pregnancy_AU = | pregnancy_US = | pregnancy_category = | legal_AU = | legal_CA = | legal_UK = | legal_US = | legal_status = | routes_of_administration = Intramuscular injection | bioavailability = | protein_bound = | metabolism = | elimination_half-life = | excretion = | CAS_number_Ref = | CAS_number = 1164-99-4 | CAS_supplemental = | ATC_prefix = | ATC_suffix = | ATC_supplemental = | PubChem = 101730066 | IUPHAR_ligand = | DrugBank_Ref = | DrugBank = | ChemSpiderID_Ref = | ChemSpiderID = 91682 | UNII = JKP2S7674A | KEGG = | ChEBI = | ChEMBL = | C=20 | H=27 | Cl=1 | O=3 | SMILES = CC(=O)OC1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CCC4=C(C(=O)CC[C@H]34)Cl)C | StdInChI_Ref = | StdInChI = 1S/C20H27ClO3/c1-11(22)24-18-8-6-16-14-3-4-15-12(5-7-17(23)19(15)21)13(14)9-10-20(16,18)2/h12-14,16,18H,3-10H2,1-2H3/t12-,13-,14-,16+,18?,20+/m1/s1 | StdInChIKey_Ref = | StdInChIKey = FNMAFGQVNCRKGS-FOMDFYGASA-N | synonyms = }}Norclostebol acetate (brand name Anabol 4-19), or norchlorotestosterone acetate (NClTA), also known as 4-chloro-19-nortestosterone 17β-acetate or as 4-chloroestr-4-en-17β-ol-3-one, is a synthetic, injectable anabolic-androgenic steroid (AAS) and derivative of 19-nortestosterone (nandrolone).[1][2][3][4][5] It is an androgen ester – specifically, the C17β acetate ester of norclostebol (4-chloro-19-nortestosterone).[1][2] See also
References1. ^1 {{cite book|author=J. Elks|title=The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies|url=https://books.google.com/books?id=0vXTBwAAQBAJ&pg=RA1-PA254|date=14 November 2014|publisher=Springer|isbn=978-1-4757-2085-3|page=254}} {{Androgens and antiandrogens}}{{Androgen receptor modulators}}{{steroid-stub}}{{genito-urinary-drug-stub}}2. ^1 {{cite book|author=Joyce H. Lowinson|title=Substance Abuse: A Comprehensive Textbook|url=https://books.google.com/books?id=HtGb2wNsgn4C&pg=PA428|year=2005|publisher=Lippincott Williams & Wilkins|isbn=978-0-7817-3474-5|pages=428–}} 3. ^{{cite book|author1=Diana Vaamonde|author2=Stefan S du Plessis|author3=Ashok Agarwal|title=Exercise and Human Reproduction: Induced Fertility Disorders and Possible Therapies|url=https://books.google.com/books?id=d86zCwAAQBAJ&pg=PA230|date=7 March 2016|publisher=Springer|isbn=978-1-4939-3402-7|pages=230–}} 4. ^{{cite journal|last1=Van Hoof|first1=N.|last2=De Wasch|first2=K.|last3=Poelmans|first3=S.|last4=Bruneel|first4=D.|last5=Spruyt|first5=S.|last6=Noppe|first6=H.|last7=Janssen|first7=C.|last8=Courtheyn|first8=D.|last9=De Brab|first9=H.|title=Norchlorotestosterone Acetate: An Alternative Metabolism Study and GC?MS2 Analysis in Kidney Fat, Urine, and Faeces|journal=Chromatographia|volume=59|issue=S1|year=2004|pages=S85–S93|issn=0009-5893|doi=10.1365/s10337-003-0178-4}} 5. ^{{cite journal | vauthors = Le Bizec B, Van Hoof N, Courtheyn D, Gaudin I, Van De Wiele M, Bichon E, De Brabander H, André F | title = New anabolic steroid illegally used in cattle-structure elucidation of 19-norchlorotestosterone acetate metabolites in bovine urine | journal = J. Steroid Biochem. Mol. Biol. | volume = 98 | issue = 1 | pages = 78–89 | year = 2006 | pmid = 16216493 | doi = 10.1016/j.jsbmb.2005.07.008 | url = }} 7 : Acetate esters|Androgen esters|Androgens and anabolic steroids|Estranes|Organochlorides|Prodrugs|World Anti-Doping Agency prohibited substances |
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