| Any | Vencedor | Segon | Tercer |
|---|
| 1945 | BEL}} André Pieters | BEL}} Albert Sercu | BEL}} Jules Huvaere |
| 1946 | BEL}} Alberic Schotte | BEL}} Jan Landuyt | BEL}} Jules Huvaere |
| 1947 | BEL}} Michel Van Elsué | BEL}} Arsene Rijckaert | BEL}} Emmanuel Thoma |
| 1948 | BEL}} Georges Desplenter | BEL}} Maurice Desimpelaere | BEL}} Albert Sercu |
| 1949 | BEL}} Michel Remue | BEL}} Georges Desplenter | BEL}} André Pieters |
| 1950 | BEL}} Albert Decin | BEL}} Robert Nolf | BEL}} Ward Van Dijck |
| 1951 | BEL}} Emmanuel Thoma | BEL}} Raphael Glorieux | BEL}} André Pieters |
| 1952 | BEL}} Karel De Baere | BEL}} Albert Ramon | BEL}} Lode Wouters |
| 1953 | BEL}} Andre Declerck | BEL}} Omer Braekevelt | BEL}} Valere Ollivier |
| 1954 | BEL}} Maurice Blomme | BEL}} Alberic Schotte | BEL}} Marcel De Mulder |
| 1955 | NED}} Wim Van Est | BEL}} Germain Derycke | BEL}} Marcel De Mulder |
| 1956 | BEL}} Germain Derycke | BEL}} Lode Anthonis | BEL}} Jos De Feyter |
| 1957 | BEL}} Noel Fore | BEL}} Joseph Schils | BEL}} Lucien Taillieu |
| 1958 | BEL}} Jos Hoevenaers | BEL}} Petrus Oellibrandt | BEL}} Frans Aerenhouts |
| 1959 | BEL}} Frans Aerenhouts | BEL}} Arthur Decabooter | BEL}} Henri Van Den Bossche |
| 1960 | BEL}} Julien Schepens | BEL}} Joseph Planckaert | BEL}} Frans De Mulder |
| 1961 | BEL}} Petrus Oellibrandt | BEL}} Jan Zagers | BEL}} Alfons Hermans |
| 1962 | BEL}} Leon Van Daele | BEL}} Rene Vanderveken | IRL}} Seamus Elliott |
| 1963 (1) | BEL}} Norbert Kerckhove | NED}} Piet van Est | NED}} Peter Post |
| 1963 (2) | BEL}} Robert Lelangue | BEL}} Willy Raes | BEL}} Clement Roman |
| 1964 | BEL}} Gilbert De Smet | ITA}} Carmine Preziosi | BEL}} Theo Nys |
| 1965 | BEL}} Jan Nolmans | BEL}} Joseph Mathy | BEL}} Julien Haelterman |
| 1966 | BEL}} Yvo Molenaers | BEL}} Albert Van Vlierberghe | BEL}} Jacques De Boever |
| 1967 | NED}} Jan Harings | BEL}} Norbert Kerckhove | BEL}} Paul In 't Ven |
| 1968 | BEL}} Jos Huysmans | BEL}} Roger Cooreman | BEL}} Roger Rosiers |
| 1969 | NED}} Wim Schepers | BEL}} Herman Vrijders | BEL}} Remi Van Vreckom |
| 1970 | BEL}} Wilfried David | BEL}} Remi Van Vreckom | BEL}} Romain Pauwels |
| 1971 | BEL}} Eric Leman | BEL}} Ronny Van De Vijver | BEL}} Julien Stevens |
| 1972 | BEL}} Christian Callens | BEL}} Fernand Bruggeman | BEL}} Georges Barras |
| 1973 | BEL}} Willy Abbeloos | BEL}} Guido Van Sweevelt | NED}} Wim Kelleners |
| 1974 | BEL}} Jose Vanackere | BEL}} Frans Mintjens | BEL}} Paul Lannoo |
| 1975 | BEL}} Jos Gijsemans | BEL}} Dirk Baert | BEL}} Willy Van Malderghem |
| 1976 | BEL}} Willem Peeters | BEL}} Ward Janssens | BEL}} Eric Van De Wiele |
| 1977 | BEL}} Ludo Peeters | BEL}} Eddy Vanhaerens | BEL}} Frans Verhaegen |
| 1978 | BEL}} Ludo Schurgers | BEL}} Walter Naegels | NED}} Martin Havik |
| 1979 | BEL}} Ludo Peeters | BEL}} Walter Godefroot | BEL}} Michel Pollentier |
| 1980 | BEL}} Lieven Malfait | BEL}} William Tackaert | BEL}} Eric Van De Wiele |
| 1981 | BEL}} Walter Planckaert | BEL}} Daniel Willems | BEL}} Filip Van De Ghinste |
| 1982 | BEL}} Gery Verlinden | BEL}} Patrick Vermeulen | BEL}} Marc Dierickx |
| 1983 | BEL}} William Tackaert | AUS}} Allan Peiper | BEL}} Luc Meersman |
| 1984 | BEL}} Patrick Versluys | BEL}} Martin Durant | BEL}} Luc Meersman |
| 1985 | BEL}} Rudy Dhaenens | BEL}} Willy Teirlinck | BEL}} Josef Lieckens |
| 1986 | BEL}} Rudy Dhaenens | BEL}} Ferdi Van Den Haute | BEL}} Herman Frison |
| 1987 | BEL}} Frans Maassen | BEL}} John De Keukelaere | BEL}} Edwin Bafcop |
| 1988 | BEL}} Johan Devos | BEL}} Peter Huyghe | BEL}} Patrick Deneu |
| 1989 | BEL}} Eddy Planckaert | BEL}} Carlo Bomans | BEL}} Pascal Elaut |
| 1990 | BEL}} Benjamin Van Itterbeeck | NED}} Adri Van Der Poel | BEL}} Dirk De Wolf |
| 1991 | NED}} Wilco Zuyderwijk | NED}} Antoine Goense | BEL}} Peter Huyghe |
| 1992 | NED}} Danny Nelissen | NED}} John Talen | BEL}} Herman Frison |
| 1993 | BEL}} Frank Van Den Abeele | RUS}} Viatcheslav Ekimov | BEL}} Paul Haghedooren |
| 1994 | BEL}} Wilfried Nelissen | BEL}} Peter Van Petegem | BEL}} Carlo Bomans |
| 1995 | BEL}} Niko Eeckhout | NED}} Leon van Bon | DEN}} Lars Michaelsen |
| 1996 | BEL}} Johan Museeuw | BEL}} Frank Vandenbroucke | BEL}} Wilfried Peeters |
| 1997 | BEL}} Franky De Buyst | BEL}} Stephane Hennebert | BEL}} Hans De Clercq |
| 1998 | BEL}} Jo Planckaert | AUS}} Patrick Jonker | NED}} Maarten den Bakker |
| 1999 | BEL}} Johan Museeuw | BEL}} Michel Van Haecke | NED}} Leon van Bon |
| 2000 | ITA}} Stefano Zanini | BEL}} Jo Planckaert | BEL}} Michel Van Haecke |
| 2001 | LAT}} Romans Vainsteins | BEL}} Jo Planckaert | BEL}} Eric De Clercq |
| 2002 | BEL}} Peter Van Petegem | BEL}} Johan Museeuw | BEL}} Tom Boonen |
| 2003 | BEL}} Johan Museeuw | BEL}} Marc Streel | BEL}} Paul Van Hyfte |
| 2004 | BEL}} Tom Boonen | BEL}} Gorik Gardeyn | BEL}} Nico Mattan |
| 2005 | BEL}} Geert Omloop | BEL}} Marc Wauters | BEL}} Nico Mattan |
| 2006 | BEL}} Leif Hoste | BEL}} Niko Eeckhout | LUX}} Frank Schleck |
| 2007 | ITA}} Alessandro Ballan | BEL}} Gorik Gardeyn | BEL}} Gianni Meersman |
| 2008 | BEL}} Stijn Devolder | BEL}} Leif Hoste | BEL}} Frederik Willems |
| 2009 | BEL}} Nick Nuyens | NED}} Steven De Jongh | BEL}} Frederik Willems |
| 2010 | BEL}} Jan Ghyselinck | BEL}} Kurt Hovelynck | BEL}} Guillaume Van Keirsbulck |
| 2011 | BEL}} Davy Commeyne | BEL}} Laurens De Vreese | BEL}} Wim De Vocht |
| 2012 | BEL}} Pieter Ghyllebert | BEL}} Guillaume Van Keirsbulck | BEL}} Frederic Verkinderen |
| 2013 | BEL}} Iljo Keisse | BEL}} Frederique Robert | BEL}} Niko Eeckhout |
| 2014 | BEL}} Jasper de Buyst | GER}} Alexander Krieger | BEL}} Jonas Van Genechten |
| 2015 | BEL}} Amaury Capiot | BEL}} Gianni Meersman | BEL}} Jelle Cant |
| 2016 | BEL}} Pieter Vanspeybrouck | GBR}} Christopher Latham | BEL}} Amaury Capiot |
| 2017 | BEL}} Iljo Keisse | NED}} Huub Duyn | BEL}} Maarten Wynants |
1. ^{{cite web | url=http://www.procyclingstats.com/race/Omloop_MandelLeieSchelde_Meulebeke_2016 | title=2016 Omloop Mandel-Leie-Schelde | work=ProCyclingStats | accessdate=10 September 2016}}
{{Cycling-race-stub}}