| 词条 | Orestrate |
| 释义 |
| Verifiedfields = | Watchedfields = | verifiedrevid = | IUPAC_name = [(8R,9S,13S,14S,17S)-17-(Cyclohexen-1-yloxy)-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-3-yl] propanoate | image = Orestrate.svg | width = 250px | tradename = | pregnancy_AU = | pregnancy_US = | pregnancy_category = | legal_AU = | legal_CA = | legal_UK = | legal_US = | legal_status = | routes_of_administration = | class = Estrogen; Estrogen ester | bioavailability = | protein_bound = | metabolism = | elimination_half-life = | excretion = | CAS_number_Ref = | CAS_number = 13885-31-9 | CAS_supplemental = | ATC_prefix = | ATC_suffix = | PubChem = 20055348 | DrugBank_Ref = | DrugBank = | ChemSpiderID_Ref = | ChemSpiderID = 16736660 | synonyms = Estradiol 3-propionate 17β-(1-cyclohexenyl) ether; 17β-(Cyclohexen-1-yloxy)-estra-1,3,5(10)-trien-3-ol propionate | C=27 | H=36 | O=3 | molecular_weight = 408.573 g/mol | SMILES = CCC(=O)OC1=CC2=C(C=C1)C3CCC4(C(C3CC2)CCC4OC5=CCCCC5)C | StdInChI = 1S/C27H36O3/c1-3-26(28)30-20-10-12-21-18(17-20)9-11-23-22(21)15-16-27(2)24(23)13-14-25(27)29-19-7-5-4-6-8-19/h7,10,12,17,22-25H,3-6,8-9,11,13-16H2,1-2H3/t22-,23-,24+,25+,27+/m1/s1 | StdInChIKey = VYAXJSIVAVEVHF-RYIFMDQWSA-N }}Orestrate ({{abbrlink|INN|International Nonproprietary Name}}), also known as estradiol 3-propionate 17β-(1-cyclohexenyl) ether, is a synthetic, steroidal estrogen and estradiol ester which was never marketed.[1][2][3][4] It is the 3-propanoyl, 17-(1-cyclohexenyl) ether and ester of estradiol.[1][3] See also
References1. ^1 {{cite book|author=J. Elks|title=The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies|url=https://books.google.com/books?id=0vXTBwAAQBAJ&pg=PA905|date=14 November 2014|publisher=Springer|isbn=978-1-4757-2085-3|pages=898, 905}} {{Estrogen receptor modulators}}{{Genito-urinary-drug-stub}}{{Steroid-stub}}2. ^{{cite book|author1=P. H. List|author2=L. Hörhammer|title=Chemikalien und Drogen Teil A: N-Q|url=https://books.google.com/books?id=4TWnBgAAQBAJ&pg=PA331|date=12 March 2013|publisher=Springer-Verlag|isbn=978-3-642-65035-2|pages=331–}} 3. ^1 {{cite book|author1=Edward B. Roche|author2=Academy of Pharmaceutical Sciences. Medicinal Chemistry Section|title=Design of biopharmaceutical properties through prodrugs and analogs: a symposium|url=https://books.google.com/books?id=T7zwAAAAMAAJ|year=1977|publisher=The Academy|isbn=978-0-917330-16-2|page=7}} 4. ^{{cite journal|last1=Galletti|first1=F.|last2=Gardi|first2=R.|title=Effect of two orally active estradiol derivatives on sulfobromphthalein retention in rats|journal=Pharmacological Research Communications|volume=6|issue=2|year=1974|pages=135–145|issn=0031-6989|doi=10.1016/S0031-6989(74)80021-4}} 6 : Abandoned drugs|Cyclohexenes|Estradiol esters|Estranes|Estrogen ethers|Synthetic estrogens |
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