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词条 Osnat Penn
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Osnat Penn ({{lang-he|אסנת פן}}) is an Israeli computational biologist. Penn is the third Israeli scientist in three years to win the UNESCO-L’Oréal fellowship, which she received in 2013 for her work on the genetic origins of autism.[1] Penn is currently at the University of Washington in Seattle.[2]

Penn has been responsible for several different computer programs developed at Tel Aviv University in order to aid in biological research.[3] GUIDANCE is a web server used for estimating alignment confidence scores.[4][5] RASER, the RAte Shift EstimatoR, is used to test site-specific evolutionary rate shifts.[6] The Pepitope Server is used to map epitopes using affinity-selected peptides.[7] Her work with autism genetic sequencing which won her the UNESCO-L’Oréal award, worked to identify where there were genetic variations that linked to individuals displaying autism.[8] Her work will also lead to prenatal screening and early diagnosis of autism.[8]

Penn has been published in Cell,[9] Genome Research,[10] Molecular Biology and Evolution,[11] Nucleic Acids Research,[5] Systematic Biology,[12] BMC Evolutionary Biology,[13] PLoS Computational Biology,[14] Bioinformatics,[15] and Proteins.[16]

References

1. ^{{Cite news|url = http://www.algemeiner.com/2013/03/29/israeli-autism-researcher-wins-unesco-fellowship/#|title = Israeli Autism Researcher Wins UNESCO Fellowship|last = |first = |date = 29 March 2013|work = Algemeiner|access-date = 26 November 2015|via = }}
2. ^{{Cite web|url = http://eichlerlab.gs.washington.edu/penno.html|title = Osnat Penn|date = |accessdate = 26 November 2015|website = Eichler Lab|publisher = University of Washington|last = |first = }}
3. ^{{Cite web|url = http://www.tau.ac.il/~penn/|title = Osnat Penn|date = |accessdate = 26 November 2015|website = Tel Aviv University|publisher = |last = |first = }}
4. ^{{Cite web|url = http://guidance.tau.ac.il/ver2/|title = The GUIDANCE Server|date = |accessdate = 26 November 2015|website = Tel Aviv University|publisher = |last = |first = }}
5. ^1 {{Cite journal|title = GUIDANCE: a web server for assessing alignment confidence scores|url = http://nar.oxfordjournals.org/content/38/suppl_2/W23|journal = Nucleic Acids Research|date = 2010-07-01|issn = 0305-1048|pmc = 2896199|pmid = 20497997|pages = W23–W28|volume = 38|issue = suppl 2|doi = 10.1093/nar/gkq443|first = Osnat|last = Penn|first2 = Eyal|last2 = Privman|first3 = Haim|last3 = Ashkenazy|first4 = Giddy|last4 = Landan|first5 = Dan|last5 = Graur|first6 = Tal|last6 = Pupko}}
6. ^{{Cite web|url = http://www.tau.ac.il/~penn/raser.html|title = RASER|date = |accessdate = 26 November 2015|website = Tel Aviv University|publisher = |last = |first = }}
7. ^{{Cite web|url = http://pepitope.tau.ac.il/|title = The Pepitope Server|date = |accessdate = 26 November 2015|website = Tel Aviv University|publisher = |last = |first = }}
8. ^1 {{Cite news|url = http://www.israelvalley.com/news/2013/03/31/39593/autisme-osnat-zomer-penn-gagne-le-prix-l-oreal-unesco-2013|title = Autisme : Osnat Zomer-Penn gagne le prix l'OREAL-UNESCO 2013|last = Kaplan|first = Michael|date = 31 March 2013|work = Israel Valley|access-date = 26 November 2015|via = |language = French}}
9. ^{{Cite journal|title = Disruptive CHD8 Mutations Define a Subtype of Autism Early in Development|journal = Cell|issn = 0092-8674|pmc = 4136921|pmid = 24998929|pages = 263–276|volume = 158|issue = 2|doi = 10.1016/j.cell.2014.06.017|first = Raphael|last = Bernier|first2 = Christelle|last2 = Golzio|first3 = Bo|last3 = Xiong|first4 = Holly A.|last4 = Stessman|first5 = Bradley P.|last5 = Coe|first6 = Osnat|last6 = Penn|first7 = Kali|last7 = Witherspoon|first8 = Jennifer|last8 = Gerdts|first9 = Carl|last9 = Baker|date = 2014-07-17}}
10. ^{{Cite journal|title = Changes in exon–intron structure during vertebrate evolution affect the splicing pattern of exons|journal = Genome Research|date = 2012-01-01|issn = 1088-9051|pmc = 3246205|pmid = 21974994|pages = 35–50|volume = 22|issue = 1|doi = 10.1101/gr.119834.110|first = Sahar|last = Gelfman|first2 = David|last2 = Burstein|first3 = Osnat|last3 = Penn|first4 = Anna|last4 = Savchenko|first5 = Maayan|last5 = Amit|first6 = Schraga|last6 = Schwartz|first7 = Tal|last7 = Pupko|first8 = Gil|last8 = Ast}}
11. ^{{Cite journal|title = Improving the Performance of Positive Selection Inference by Filtering Unreliable Alignment Regions|url = http://mbe.oxfordjournals.org/content/29/1/1|journal = Molecular Biology and Evolution|date = 2012-01-01|issn = 0737-4038|pmid = 21772063|pages = 1–5|volume = 29|issue = 1|doi = 10.1093/molbev/msr177|first = Eyal|last = Privman|first2 = Osnat|last2 = Penn|first3 = Tal|last3 = Pupko}}
12. ^{{Cite journal|title = An Evolutionary Analysis of Lateral Gene Transfer in Thymidylate Synthase Enzymes|url = http://sysbio.oxfordjournals.org/content/59/2/212|journal = Systematic Biology|date = 2010-03-01|issn = 1063-5157|pmc = 2826268|pmid = 20525631|pages = 212–225|volume = 59|issue = 2|doi = 10.1093/sysbio/syp104|first = Adi|last = Stern|first2 = Itay|last2 = Mayrose|first3 = Osnat|last3 = Penn|first4 = Shaul|last4 = Shaul|first5 = Uri|last5 = Gophna|first6 = Tal|last6 = Pupko}}
13. ^{{Cite journal|title = Rodent phylogeny revised: analysis of six nuclear genes from all major rodent clades|journal = BMC Evolutionary Biology|date = 2009-04-02|issn = 1471-2148|pmc = 2674048|pmid = 19341461|pages = 71|volume = 9|issue = 1|doi = 10.1186/1471-2148-9-71|first = Shani|last = Blanga-Kanfi|first2 = Hector|last2 = Miranda|first3 = Osnat|last3 = Penn|first4 = Tal|last4 = Pupko|first5 = Ronald W.|last5 = DeBry|first6 = Dorothée|last6 = Huchon}}
14. ^{{Cite journal|title = Evolutionary Modeling of Rate Shifts Reveals Specificity Determinants in HIV-1 Subtypes|journal = PLoS Comput Biol|date = 2008-11-07|pmc = 2566816|pmid = 18989394|pages = e1000214|volume = 4|issue = 11|doi = 10.1371/journal.pcbi.1000214|first = Osnat|last = Penn|first2 = Adi|last2 = Stern|first3 = Nimrod D.|last3 = Rubinstein|first4 = Julien|last4 = Dutheil|first5 = Eran|last5 = Bacharach|first6 = Nicolas|last6 = Galtier|first7 = Tal|last7 = Pupko}}
15. ^{{Cite journal|title = Pepitope: epitope mapping from affinity-selected peptides|url = http://bioinformatics.oxfordjournals.org/content/23/23/3244|journal = Bioinformatics|date = 2007-12-01|issn = 1367-4803|pmid = 17977889|pages = 3244–3246|volume = 23|issue = 23|doi = 10.1093/bioinformatics/btm493|first = Itay|last = Mayrose|first2 = Osnat|last2 = Penn|first3 = Elana|last3 = Erez|first4 = Nimrod D.|last4 = Rubinstein|first5 = Tomer|last5 = Shlomi|first6 = Natalia Tarnovitski|last6 = Freund|first7 = Erez M.|last7 = Bublil|first8 = Eytan|last8 = Ruppin|first9 = Roded|last9 = Sharan}}
16. ^{{Cite journal|title = Stepwise prediction of conformational discontinuous B-cell epitopes using the Mapitope algorithm|journal = Proteins: Structure, Function, and Bioinformatics|date = 2007-07-01|issn = 1097-0134|pages = 294–304|volume = 68|issue = 1|doi = 10.1002/prot.21387|pmid = 17427229|first = Erez M.|last = Bublil|first2 = Natalia Tarnovitski|last2 = Freund|first3 = Itay|last3 = Mayrose|first4 = Osnat|last4 = Penn|first5 = Anna|last5 = Roitburd-Berman|first6 = Nimrod D.|last6 = Rubinstein|first7 = Tal|last7 = Pupko|first8 = Jonathan M.|last8 = Gershoni|citeseerx = 10.1.1.124.9174}}

External links

  • Official site
{{Authority control}}{{DEFAULTSORT:Penn, Osnat}}

6 : Israeli women scientists|L'Oréal-UNESCO Awards for Women in Science fellows|Israeli biologists|21st-century women scientists|Year of birth missing (living people)|Living people
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