词条 | Ovandrotone |
释义 |
| Verifiedfields = | Watchedfields = | verifiedrevid = | IUPAC_name = 3- | image = Ovandrotone.svg | width = 250 | tradename = | pregnancy_AU = | pregnancy_US = | pregnancy_category = | legal_AU = | legal_CA = | legal_UK = | legal_US = | legal_status = | routes_of_administration = | bioavailability = | protein_bound = | metabolism = | elimination_half-life = | excretion = | CAS_number_Ref = | CAS_number = 40845-00-9 | CAS_supplemental = | ATC_prefix = | ATC_suffix = | ATC_supplemental = | PubChem = 20538550 | IUPHAR_ligand = | DrugBank_Ref = | DrugBank = | ChemSpiderID = 59650713 | UNII = | KEGG = | ChEBI = | ChEMBL = | C=22 | H=30 | O=4 | S=1 | SMILES = C[C@]12CC[C@H]3[C@H]([C@@H]1CCC2=O)[C@@H](CC1=CC(=O)CC[C@]31C)SCCC(O)=O | StdInChI_Ref = | StdInChI = 1S/C22H30O4S/c1-21-8-5-14(23)11-13(21)12-17(27-10-7-19(25)26)20-15-3-4-18(24)22(15,2)9-6-16(20)21/h11,15-17,20H,3-10,12H2,1-2H3,(H,25,26)/t15-,16-,17+,20-,21?,22?/m0/s1 | StdInChIKey_Ref = | StdInChIKey = OZLABWUNIWIISO-DHEJPUEPSA-N | synonyms = Androstenedione-7α-carboxyethylthioether; 3-[(3,17-Dioxoandrost-4-en-7α-yl)thio]propanoic acid }}Ovandrotone, also known as androstenedione-7α-carboxyethylthioether,[1] is a synthetic androstane steroid and the C7α carboxyethylthioether of androstenedione.[2] It is a component of ovandrotone albumin (Fecundin), a conjugate of androstenedione and human serum albumin and an immunogen and vaccine against androstenedione that is used to generate androgen immunity and thereby increase the ovulation rate and number of lambs born to ewes.[3][4] References1. ^{{cite book|title=Journal of Animal Science|url=https://books.google.com/books?id=nbqzAAAAIAAJ|year=1991|publisher=American Society of Animal Science|pages=3931–3932}} {{steroid-stub}}{{genito-urinary-drug-stub}}2. ^{{cite book|author=J. Elks|title=The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies|url=https://books.google.com/books?id=0vXTBwAAQBAJ&pg=RA1-PA908|date=14 November 2014|publisher=Springer|isbn=978-1-4757-2085-3|page=908}} 3. ^{{cite journal|last1=Hoskinson|first1=R. M.|last2=Scaramuzzi|first2=R. J.|last3=Campbell|first3=B. K.|last4=Downing|first4=J. A.|last5=Welch|first5=R. J.|last6=Harrison|first6=B. E.|title=Effects of Antibodies to Steroid Hormones on Reproductive Events of Sheep and Cattle|year=1986|pages=351–366|doi=10.1007/978-1-4684-5140-5_38}} 4. ^{{cite journal|last1=Carnegie|first1=Patrick R.|title=Autoimmunization Against Hormones: A New Strategy in Animal Production|year=1988|pages=245–254|doi=10.1007/978-1-4612-3734-1_15}} 4 : Androstanes|Diketones|Thioethers|Veterinary drugs |
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