“Prickle planar cell polarity protein 2”的意思、由来-开放百科全书

词条

Prickle planar cell polarity protein 2

释义

Function
References
Further reading

Prickle planar cell polarity protein 2 is a protein that in humans is encoded by the PRICKLE2 gene.

^[1]

Function

This gene encodes a homolog of Drosophila prickle. The exact function of this gene is not known, however, studies in mice suggest that it may be involved in seizure prevention. Mutations in this gene are associated with progressive myoclonic epilepsy type 5. [provided by RefSeq, Dec 2011].

References

1. ^{{cite web| title = Entrez Gene: Prickle planar cell polarity protein 2| url = https://www.ncbi.nlm.nih.gov/gene/166336| accessdate = 2018-02-20}}

{{cite journal |vauthors=Katoh M, Katoh M |title=Identification and characterization of human PRICKLE1 and PRICKLE2 genes as well as mouse Prickle1 and Prickle2 genes homologous to Drosophila tissue polarity gene prickle |journal=Int. J. Mol. Med. |volume=11 |issue=2 |pages=249–56 |date=February 2003 |pmid=12525887 |doi= |url= |author=}}
{{cite journal |vauthors=Daulat AM, Luu O, Sing A, Zhang L, Wrana JL, McNeill H, Winklbauer R, Angers S |title=Mink1 regulates β-catenin-independent Wnt signaling via Prickle phosphorylation |journal=Mol. Cell. Biol. |volume=32 |issue=1 |pages=173–85 |date=January 2012 |pmid=22037766 |pmc=3255712 |doi=10.1128/MCB.06320-11 |url= |author=}}

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Function

References

Further reading