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词条 Pseudoalleles
释义

  1. References

Pseudoallelism is a state in which two genes with similar functions are located so close to one another on a chromosome that they are genetically linked.[1][2] This means that the two genes (pseudoalleles) are nearly always inherited together. Since the two genes have related functions, they may appear to act as a single gene. In rare cases, the two linked pseudoalleles can be separated, or recombined. One hypothesis is that pseudoalleles are formed as a result of gene duplication events, and the duplicated genes can undergo gene evolution to develop new functions.

Characteristic of Pseudoalleles:

  1. These are closely linked allele within which crossing over occur.
  2. They affect the same character.

Example:

Red eye colour of Drosophila has different mutants like white and apricot.They affect pigmentation i.e., affect the same character.So, they are allelic.They can undergo recombination,i.e.,they are nonallelic.

References

1. ^{{cite journal|last1=Morange|first1=M|title=Pseudoalleles and Gene Complexes: The Search for the Elusive Link Between Genome Structure and Gene Function|journal=Perspectives in Biology and Medicine|date=2015|volume=58|issue=2|pages=196–204|pmid=26750602|doi=10.1353/pbm.2015.0027}}
2. ^{{cite journal|last1=Welshons|first1=WJ|last2=Von Halle|first2=ES|title=Pseudoallelism at the notch locus in drosophila.|journal=Genetics|date=June 1962|volume=47|pages=743–59|pmid=14006076|pmc=1210367}}

1 : Genetics

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