| 词条 | PSNCBAM-1 |
| 释义 |
| verifiedrevid = | IUPAC_name = 1-(4-chlorophenyl)-3-(3-(6-(pyrrolidin-1-yl)pyridin-2-yl)phenyl)urea | image = PSNCBAM-1.png | tradename = | legal_status = | routes_of_administration = | metabolism = | elimination_half-life = | excretion = | IUPHAR_ligand = | CAS_number = 877202-74-9 | PubChem = 11560249 | ChemSpiderID = 9735023 | C=22 | H=21 | N=4 | O=1 | Cl=1 | molecular_weight = | smiles = Clc1ccc(NC(=O)Nc2cccc(c2)c3cccc(n3)N4CCCC4)cc1 | StdInChI = 1S/C22H21ClN4O/c23-17-9-11-18(12-10-17)24-22(28)25-19-6-3-5-16(15-19)20-7-4-8-21(26-20)27-13-1-2-14-27/h3-12,15H,1-2,13-14H2,(H2,24,25,28) | StdInChIKey = HDAYFSFWIPRJSO-UHFFFAOYSA-N }}PSNCBAM-1 is a negative allosteric modulator of the cannabinoid CB1 receptor.[1][2] See also
References1. ^{{cite journal | title=Diarylureas as Allosteric Modulators of the Cannabinoid CB1 Receptor: Structure–Activity Relationship Studies on 1-(4-Chlorophenyl)-3- {{Cannabinoids}}{{Cannabinoidergics}}{{cannabinoid-stub}}2. ^{{cite journal | title=PSNCBAM-1, a novel allosteric antagonist at cannabinoid CB1 receptors with hypophagic effects in rats |vauthors=Horswill JG, Bali U, Shaaban S, Keily JF, Jeevaratnam P, Babbs AJ, Reynet C, Wong Kai In P | journal=British Journal of Pharmacology | date=November 2007 | volume=152 | issue=5 | pages=805–814 | doi=10.1038/sj.bjp.0707347 | pmid=17592509 | pmc=2190018}} 2 : Cannabinoids|CB1 receptor antagonists |
| 随便看 |
|
开放百科全书收录14589846条英语、德语、日语等多语种百科知识，基本涵盖了大多数领域的百科知识，是一部内容自由、开放的电子版国际百科全书。