“PTS Galactitol Family”的意思、由来-开放百科全书

The PTS Galactitol (Gat) Family (TC# 4.A.5) is part of the PTS-AG superfamily. The biochemistry of this family is poorly defined. The only well-characterized member of this family is the galactitol permease of Escherichia coli.^[1] However, a homologous IIC protein from Listeria monocytogenes has been shown to be required for D-arabitol fermentation.^[2] It presumably functions together with IIA^Gat and IIB^Gat homologues. IIC^Gat is distantly related to IIC^Sgc of E. coli; IIA^Gat is distantly related to IIA^Sga and IIA^Sgcof E. coli as well as IIA^Mtl and IIA^Fru. IIB^Gat is distantly related to IIB^Sga and IIB^Sgc of E. coli.^[3] Domains in the LicR/CelR family of transcriptional activators show C-terminal domains exhibiting weak sequence similarity to IIB^Gat and IIA^Gat.^[4]

1. ^{{Cite journal|last=Nobelmann|first=Barbara|date=17 May 1995|title=Sequence of the gat operon for galactitol utilization from a wild-type strain EC3132 of Escherichia coli.|url=|journal=Biochim Biophys Acta|volume=1262|issue=|doi=10.1016/0167-4781(95)00053-j|pmid=7772602|via=|pages=69–72}}
2. ^{{Cite journal|last=Saklani-Jusforgues|first=H.|last2=Fontan|first2=E.|last3=Goossens|first3=P. L.|date=2001-03-01|title=Characterisation of a Listeria monocytogenes mutant deficient in D-arabitol fermentation|journal=Research in Microbiology|volume=152|issue=2|pages=175–177|issn=0923-2508|pmid=11316371|doi=10.1016/s0923-2508(01)01189-5}}
3. ^{{Cite journal|last=Reizer|first=Jonathan|date=Apr 1995|title=Novel phosphotransferase system genes revealed by bacterial genome analysis--a gene cluster encoding a unique Enzyme I and the proteins of a fructose-like permease system|url=|journal=Microbiology|volume=141|issue=4|doi=10.1099/13500872-141-4-961|pmid=7773398|via=|pages=961–71}}
4. ^{{Cite journal|last=Tchieu|first=J. H.|last2=Norris|first2=V.|last3=Edwards|first3=J. S.|last4=Saier|first4=M. H.|date=2001-07-01|title=The complete phosphotransferase system in Escherichia coli|journal=Journal of Molecular Microbiology and Biotechnology|volume=3|issue=3|pages=329–346|issn=1464-1801|pmid=11361063}}

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