| 词条 | RMBase (RNA Modification Base) |
| 释义 |
|title = RMBase |logo = |description= decoding the landscape of RNA modifications identified from high-throughput sequencing datasets. |scope = |organism = |center = Sun Yat-sen University |laboratory = Key Laboratory of Gene Engineering of the Ministry of Education |author = Jian-Hua Yang |citation = Sun & al. (2015)[1] |released = 2010 |standard = |format = |url = http://rna.sysu.edu.cn/rmbase/ |download = |webservice = |sql = |sparql = |webapp = |standalone = |license = |versioning = |frequency = |curation = |bookmark = |version= }}RMBase (RNA Modification Base) [2][3] is designed for decoding the landscape of RNA modifications identified from high-throughput sequencing data (MeRIP-seq, m6A-seq, miCLIP, m6A-CLIP, Pseudo-seq, Ψ-seq, CeU-seq, Aza-IP, RiboMeth-seq). It contains ~124200 N6-Methyladenosines (m6A), ~9500 pseudouridine (Ψ) modifications, ~1000 5-methylcytosine (m5C) modifications, ~1210 2′-O-methylations (2′-O-Me) and ~3130 other types of RNA modifications. RMBase demonstrated thousands of RNA modifications located within mRNAs, regulatory ncRNAs (e.g. lncRNAs, miRNAs, pseudogenes, circRNAs, snoRNAs, tRNAs), miRNA target sites and disease-related SNPs. See also
References1. ^{{cite journal|last1=Sun|first1=WJ|last2=Li|first2=JH|last3=Liu|first3=S|last4=Wu|first4=J|last5=Zhou|first5=H|last6=Qu|first6=LH|last7=Yang|first7=JH|title=RMBase: a resource for decoding the landscape of RNA modifications from high-throughput sequencing data.|journal=Nucleic Acids Research|date=11 October 2015|pmid=26464443|doi=10.1093/nar/gkv1036|pages=gkv1036|pmc=4702777|volume=44}} 2. ^{{cite journal|last1=Sun|first1=WJ|last2=Li|first2=JH|last3=Liu|first3=S|last4=Wu|first4=J|last5=Zhou|first5=H|last6=Qu|first6=LH|last7=Yang|first7=JH|title=RMBase: a resource for decoding the landscape of RNA modifications from high-throughput sequencing data.|journal=Nucleic Acids Research|date=11 October 2015|pmid=26464443|doi=10.1093/nar/gkv1036|pages=gkv1036|pmc=4702777|volume=44}} 3. ^{{cite journal|last1=Xuan|first1=JJ|last2=Sun|first2=WJ|last3=Lin|first3=PH|last4=Zhou|first4=KR|last5=Liu|first5=S|last6=Zheng|first6=LL|last7=Qu|first7=LH|last8=Yang|first8=JH|title=RMBase v2.0: deciphering the map of RNA modifications from epitranscriptome sequencing data.|journal=Nucleic Acids Research|date=4 January 2018|volume=46|issue=D1|pages=D327-D334|doi=10.1093/nar/gkx934|pmid=29040692}} External links
4 : Biological databases|RNA|MicroRNA|LncRNA |
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