| 词条 | Rudi Cormane |
| 释义 |
| honorific_prefix = | honorific_suffix = | image = Rudi Cormane.jpg | image_size = | alt = | caption = | birth_name = | birth_date = {{birth date|1925|04|07|df=y}} | birth_place = Bandung, Indonesia | death_date = {{death date and age|1987|02|18|1925|04|07|df=y}} | death_place = | nationality = | citizenship = | education = University of Leiden | occupation = | years_active = | known_for = Research in immunofluorescence | relations = | website = | profession = Dermatologist | field = | work_institutions = {{hlist|University of Leiden| University of Utrecht}} | specialism = Autoimmune skin disease | research_field = | notable_works = | prizes = | child = | module2 = | signature = }} Rudi Harold Cormane (7 April 1925 – 18 February 1987) was a Dutch dermatologist who pioneered research in immunofluorescence studies of the skin. During the Second World War he was interned in a Japanese camp where he received an education from other prisoners. After the war he gained entry to the University of Leiden in the Netherlands to study medicine, but it was interrupted in 1947 when an epidemic of polio caused paralysis of his legs. He trained in dermatology at Leiden, eventually becoming the head of the Department of Dermatology at the University of Utrecht. Throughout his career, he did pioneering work in the then new developments in immunofluorescence studies of the skin, and much research in the Autoimmune skin disease origin of many skin diseases including lupus erythematosus, dermatitis herpetiformis and many autoimmune bullous diseases. Early life and educationCormane was born on 7 April 1925 in Bandung, Indonesia, to a manager of a plantation and his wife. At the time, the region was known as the Dutch East Indies.[1][2] By 1942, the Second World War had extended to the area, and Cormane was imprisoned in a Japanese camp. Here, older prisoners provided him with sufficient education to enable him to enter the University of Leiden in 1946. He graduated in 1953.[1] His studies were interrupted after he contracted polio during a 1947 epidemic which necessitated intensive treatment in Switzerland for paralysis of his legs.[1] CareerIn 1956, Cormane established the Laboratory of Fungal Diseases of the Department of Dermatology at the Department of Microbial Diseases, headed by W.R.O. Goslings. Here, he researched and wrote his thesis on "Candida albicans en de therapie met antibiotica" (Candida albicans and treatment with antibiotics). After graduation, he trained at the Department of Internal Medicine at the University of Leiden when it was headed by J. Mulder and A. Querido, being appointed to its staff as a specialist in 1958. In 1960, the Head of the Department of Dermatology at the University of Utrecht, L. H. Jansen, invited Cormane to become a resident, following which he became a specialist in dermatology and venereology, and was three years later appointed to its staff.[1] He authored many articles on enzyme histochemical studies of the skin and nephelometric studies of serum in drug allergy between 1956 and 1963.[1] ImmunofluorescenceCormane became active in the then new developments in immunofluorescence studies of the skin, resulting in his classic article in 1964, “Bound globulin in the skin of patients with chronic discoid lupus erythematosus and systemic lupus erythematosus". He pioneered much research in the autoimmune origin of many skin diseases including lupus erythematosus, pemphigus, pemphigoid, and other autoimmune bullous diseases.[1] He was appointed chairman of the Department of Dermatology at the Binnengasthuis, University of Amsterdam professor in dermatology and venereology in 1967, and in the same year, reported his initial results of immunoglobulin deposition in the skin in dermatitis herpetiformis, proving the deposition of IgA in the skin of these people.[3] Often invited to speak internationally, one memorable visit was in 1982 when, as a former prisoner of war, he was invited to Japan.[1] PersonalCormane enjoyed music and played the flute. He also kept a collection of cloisonné pottery. He never married.[1] Death and legacyCormane co-founded the European Society of Dermatological Research, the annual meetings initially always took place in Amsterdam to avoid "scientific tourism." The Rudi Cormane Lecture is given in his honour.[1] Cormane's plan was to retire to Thailand; however, he died from a cardiac arrest on 18 February 1987.[1] Selected publicationsBooks
Articles
References1. ^1 2 3 4 5 6 7 8 9 [https://www.ncbi.nlm.nih.gov/pubmed/19168006 "Rudi Harold Cormane (1925-1987): A Fabulous Researcher and Clinician"], Clinics in Dermatology, Vol. 27 (2009), pp. 237–9. via PubMed {{subscription required}} {{authority control}}{{DEFAULTSORT:Cormane, Rudi}}2. ^{{cite book|author1=Crissey, John Thorne|author2=Lawrence C. Parish|author3=Karl Holubar.|title=Historical Atlas of Dermatology and Dermatologists|url=https://books.google.com/books?id=7ThZDwAAQBAJ&pg=PA178|year=2013|place=Boca Raton|publisher=CRC Press|isbn=978-1-84184-864-8|page=178}} 3. ^[https://books.google.com/books?id=QHAeBAAAQBAJ&pg=PA6 "Historical background"] by Karl Holubar in {{cite book|author=Robert A. Briggaman & Fenella Wojnarowska.|title=Management of Blistering Diseases|url=|year=1990|publisher=Springer|location=Dordrecht|isbn=978-1-4899-7190-6|page=6}} 8 : 1925 births|1987 deaths|Dutch dermatologists|Leiden University alumni|Dutch people with disabilities|Utrecht University faculty|20th-century Dutch East Indies people|University of Amsterdam faculty |
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