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词条 Ruth R. Wexler
释义

  1. Education

  2. Research

  3. Awards

  4. References

Ruth Wexler is an American industrial chemist best known as a co-discoverer of apixaban, a marketed anticoagulant; and losartan, a blood pressure treatment.[1]{{Infobox scientist
| name = Ruth R. Wexler, Ph.D.
| birth_place = Pikesville, MD
| death_date =
| nationality = American
| alma_mater = University of Pennsylvania
| thesis_year = 1982
| doctoral_advisor = Amos Smith
| known_for = cardiovascular drug development
| spouse =
}}

Education

Wexler received her B.A. in Chemistry from Boston University in 1977, and a Ph.D. in organic chemistry working with Amos B. Smith at the University of Pennsylvania in 1982.[2][3]

Research

Wexler started her career at DuPont in 1982, rising to Executive Director in 1998. She then joined Bristol-Myers Squibb as an Executive Director in 2001, moving eventually to New Jersey to head their cardiovascular research unit.[2] She has worked on targets involved in apoptosis, inflammation, obesity, and coagulation. As of 2018, she has over 215 original research publications.[4]

Awards

  • 2015 - E.B. Hershberg Award for Discoveries in Medicinally Active Substances[1]
  • 2014 - Inducted into the ACS MEDI Hall of Fame[5]
  • 2011 - BMS Ondetti and Cushman Award
  • 2004 - Outstanding New Jersey Woman in Research

References

1. ^{{Cite web|url=https://cen.acs.org/articles/93/i9/E-B-Hershberg-Award-Important.html|title=E. B. Hershberg Award For Important Discoveries In Medicinally Active Substances {{!}} Chemical & Engineering News|last=Jarvis|first=Lisa|website=cen.acs.org|access-date=2018-11-21}}
2. ^{{Cite web|url=https://www.acsmedchem.org/?nd=Wexler|title=Ruth R. Wexler, Ph.D.|last=2018|first=2014|website=www.acsmedchem.org|access-date=2018-11-21}}
3. ^{{Cite web|url=https://www.sas.upenn.edu/smith-group/content/wexler-ruth|title=Wexler, Ruth {{!}} Amos Smith Research Group|website=www.sas.upenn.edu|language=en|access-date=2018-11-21}}
4. ^{{Cite journal|last=Quan|first=Mimi L.|last2=Pinto|first2=Donald J. P.|last3=Smallheer|first3=Joanne M.|last4=Ewing|first4=William R.|last5=Rossi|first5=Karen A.|last6=Luettgen|first6=Joseph M.|last7=Seiffert|first7=Dietmar A.|last8=Wexler|first8=Ruth R.|date=2018-05-18|title=Factor XIa Inhibitors as New Anticoagulants|journal=Journal of Medicinal Chemistry|language=en|volume=61|issue=17|pages=7425–7447|doi=10.1021/acs.jmedchem.8b00173|pmid=29775297|issn=0022-2623}}
5. ^{{Cite web|url=https://www.acsmedchem.org/?nd=inductees|title=MEDI Hall of Fame Inductees|last=2018|first=2014|website=www.acsmedchem.org|access-date=2018-11-21}}
{{DEFAULTSORT:Wexler, Ruth R.}}

6 : Living people|Year of birth missing (living people)|American women chemists|Organic chemists|Boston University alumni|University of Pennsylvania alumni

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