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词条 Sabin Vaccine Institute
释义

  1. Background

  2. Vaccine development and research

  3. Neglected tropical diseases

  4. Advocacy and education

  5. Board of directors

  6. Gold medal award

  7. References

  8. External links

{{Infobox organization
| name = Sabin Vaccine Institute
| native_name =
| native_name_lang =
| named_after = Albert B. Sabin
| image = Sabinlogo-highres.jpg
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| established = {{start date and age|1993}}
| founders ={{ublist|

Heloisa Sabin|

H.R. Shepherd|

Robert M. Chanock|

Philip Russell}}


| founding_location =
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| type = Charitable organization
| status =
| purpose = vaccination and disease prevention
| professional_title =
| headquarters = Washington, D.C.
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| leader_title = CEO
| leader_name = Amy Finan
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| website = {{URL|http://www.sabin.org}}
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Sabin Vaccine Institute (Sabin), located in Washington, D.C., is a nonprofit (501(c)(3)) organization promoting global vaccine development, availability, and use. Through its work, Sabin hopes to reduce human suffering by preventing the spread of vaccine-preventable, communicable disease in humans through herd immunity, and also hopes to mitigate the poverty caused by these diseases.

Background

Founded in 1993[1][2] in honor of its eponym, Albert B. Sabin, creator of the oral polio vaccine, Sabin works to reduce "human suffering from vaccine-preventable and neglected tropical diseases (NTDs)."[3] The organization endeavors to reach its goal via its three main programs: Sabin Vaccine Development, the Global Network for Neglected Tropical Diseases, and Vaccine Advocacy and Education.[4] Through its Product Development Partnership (PDP), Sabin has worked with organizations such as King Saud University,[5] Texas Children's Hospital Center,[6] International Vaccine Institute,[7] and George Washington University School of Medicine & Health Sciences[8] toward its goals, with funding and support from the Bill & Melinda Gates Foundation,[8][10] the National Institute of Allergy and Infectious Diseases,[11] the Dutch Ministry of Foreign Affairs,[12] the Brazilian Ministry of Health[12] and other benefactors.

Vaccine development and research

In 2012, Sabin partnered with International Vaccine Institute to combine their research, development, and promotion efforts in Asia, Africa, and the Americas.[7]

Sabin is currently working on multiple vaccines for humans[3] including vaccines for Hookworm infection (Na-GST-1, Na-APR-1),[12][8][18][19] Schistosomiasis (Sm-TSP-2),[20][21][22][23] Chagas disease (Tc24, TSA-1),[24][6][26] Leishmaniasis (Ld-NH36, PdSP15),[27][28][29] Severe acute respiratory syndrome (SARS)/Middle East respiratory syndrome (MERS) (Pan-β-CoVax),[30][31][32] Soil-transmitted helminthiasis (STH),[33][34] and Onchocerciasis (Ov-103, Ov-RAL-2).[35][36][37][38][35]

Neglected tropical diseases

In 2006, Sabin co-founded the Global Network for Neglected Tropical Diseases in order "to raise the awareness, political will and funding necessary to control and eliminate the most common NTDs."[40] Through its work on NTDs, Sabin hopes to reduce poverty caused by these diseases as many of them have been shown to adversely affect "childhood cognitive development among the poor, thereby reinforcing poverty."[41]

Advocacy and education

Sabin works with experts and organizations from around the world to advance knowledge of both infectious diseases and the vaccines that can prevent them. Through the International Association of Immunization Managers (IAIM) Network, Sabin arranges international forums to improve the success rates of immunization programs.[4] Sabin serves as the Secretariat for the Coalition against Typhoid whose mission is to raise awareness of Typhoid and Salmonellosis.[43]

Board of directors

  • Axel Hoos (Chairman)
  • Amy Finan (Ex Officio Trustee)
  • Peter L. Thoren (Vice Chairman)
  • Wendy Commins Holman
  • Kenneth Kelley
  • Paul Maddon
  • Michael W. Marine
  • Regina Rabinovich
  • Philip K. Russell (past Chairman)
  • Heloisa Sabin (In Memoriam of Founding Member and Honorary Trustee)
  • H. R. Shepherd (In Memoriam of the Founding Chairman)

Gold medal award

{{main|Albert B. Sabin Gold Medal}}

First awarded in 1994, the Albert B. Sabin Gold Medal is presented by Sabin each year to one or more persons who have made a major contribution to the field of vaccinology or related fields. The award is given in honor of the work of Albert B. Sabin.[45] Past recipients of the award include Samuel L. Katz (2003), Joseph L. Melnick (1996), and Ruth S. Nussenzweig (2008).[46]

References

1. ^1 {{cite web|title=In Memoriam: Heloisa Sabin|url=http://www.sabin.org/updates/pressreleases/memoriam-heloisa-sabin|website=Sabin|accessdate=6 September 2017|language=en}}
2. ^1 {{cite web|title=The Legacy of Albert B. Sabin|url=http://www.sabin.org/legacy-albert-b-sabin|website=Sabin|accessdate=6 September 2017|language=en}}
3. ^1 2 {{cite web|title=SABIN Vaccine Institute|url=https://michelsonmedical.org/who-we-are/beneficiaries/sabin-vaccine-institute/|website=Michelson Medical Research Foundation|accessdate=2 September 2017}}
4. ^1 2 {{cite web|title=Immunization Manager Network|url=http://www.sabin.org/programs/immunization-manager-network|website=Sabin|accessdate=2 September 2017|language=en}}
5. ^1 {{cite web|title=Sabin PDP, King Saud University Sign Project Agreement to Build Vaccine Research and Development Capacity in Saudi Arabia|url=https://sa.usembassy.gov/sabin-pdp-king-saud-university-sign-project-agreement-to-build-vaccine-research-and-development-capacity-in-saudi-arabia/|website=U.S. Embassy & Consulates in Saudi Arabia|accessdate=9 September 2017|archiveurl=https://web.archive.org/web/20170909002852/https://sa.usembassy.gov/sabin-pdp-king-saud-university-sign-project-agreement-to-build-vaccine-research-and-development-capacity-in-saudi-arabia/|archivedate=9 September 2017|date=16 November 2015}}
6. ^1 2 {{cite web|title=IVI and Sabin Vaccine Institute Form a Strategic Alliance to Develop Vaccines for the World’s Poor|url=http://www.ivi.int/?mod=document&uid=276&page_id=12426|website=International Vaccine Institute|accessdate=6 September 2017|archiveurl=https://web.archive.org/web/20170906202653/http://www.ivi.int/?mod=document&uid=276&page_id=12426|archivedate=6 September 2017|date=18 July 2012}}
7. ^1 2 3 {{cite journal|last1=Hotez|first1=Peter J.|last2=Diemert|first2=David|last3=Bacon|first3=Kristina M.|last4=Beaumier|first4=Coreen|last5=Bethony|first5=Jeffrey M.|last6=Bottazzi|first6=Maria Elena|last7=Brooker|first7=Simon|last8=Couto|first8=Artur Roberto|last9=da Silva Freire|first9=Marcos|last10=Homma|first10=Akira|last11=Lee|first11=Bruce Y.|last12=Loukas|first12=Alex|last13=Loblack|first13=Marva|last14=Morel|first14=Carlos Medicis|last15=Oliveira|first15=Rodrigo Correa|last16=Russell|first16=Philip K.|title=The Human Hookworm Vaccine|journal=Vaccine|date=18 April 2013|volume=31|issue=Suppl 2|pages=B227–B232|doi=10.1016/j.vaccine.2012.11.034|pmc=3988917|issn=0264-410X}}
8. ^1 2 3 {{cite web|title=Hookworm Vaccine Research|url=https://www.gatesfoundation.org/Media-Center/Press-Releases/2000/08/Hookworm-Vaccine-Research|website=Bill & Melinda Gates Foundation|accessdate=8 September 2017|archiveurl=https://web.archive.org/web/20150911144857/http://www.gatesfoundation.org/Media-Center/Press-Releases/2000/08/Hookworm-Vaccine-Research|archivedate=11 September 2015|language=en}}
9. ^1 {{cite web|title=Status of Vaccine Research and Development of Vaccines for Human Hookworm Infection|url=http://www.who.int/immunization/research/meetings_workshops/Human_hookworm_infection_vaccineRD_Sept2014.pdf|website=World Health Organization|accessdate=8 September 2017|archiveurl=https://web.archive.org/web/20170830045043/http://www.who.int/immunization/research/meetings_workshops/Human_hookworm_infection_vaccineRD_Sept2014.pdf|archivedate=30 August 2017}}
10. ^1 {{cite journal|last1=Tebeje|first1=Biniam Mathewos|last2=Harvie|first2=Marina|last3=You|first3=Hong|last4=Loukas|first4=Alex|last5=McManus|first5=Donald P.|title=Schistosomiasis vaccines: where do we stand?|journal=Parasites & Vectors|date=30 September 2016|volume=9|pages=528|doi=10.1186/s13071-016-1799-4|url=https://parasitesandvectors.biomedcentral.com/articles/10.1186/s13071-016-1799-4|accessdate=8 September 2017|issn=1756-3305}}
11. ^1 {{cite journal|last1=Merrifield|first1=Maureen|last2=Hotez|first2=Peter J.|last3=Beaumier|first3=Coreen M.|last4=Gillespie|first4=Portia|last5=Strych|first5=Ulrich|last6=Hayward|first6=Tara|last7=Bottazzi|first7=Maria Elena|title=Advancing a vaccine to prevent human schistosomiasis|journal=Vaccine|date=3 June 2016|volume=34|issue=26|pages=2988–2991|doi=10.1016/j.vaccine.2016.03.079|pmid=27036511|issn=1873-2518}}
12. ^1 {{cite journal|last1=Beaumier|first1=Coreen M.|last2=Gillespie|first2=Portia M.|last3=Strych|first3=Ulrich|last4=Hayward|first4=Tara|last5=Hotez|first5=Peter J.|last6=Bottazzi|first6=Maria Elena|title=Status of vaccine research and development of vaccines for Chagas disease|journal=Vaccine|date=3 June 2016|volume=34|issue=26|pages=2996–3000|doi=10.1016/j.vaccine.2016.03.074|pmid=27026146|issn=1873-2518}}
13. ^1 2 {{cite web|title=Texas Children's Hospital Center for Vaccine Development awarded grant to develop therapeutic vaccine for chagas disease|url=http://www.klebergfoundation.org/texas-childrens-hospital-center-for-vaccine-development-awarded-grant-to-develop-therapeutic-vaccine-for-chagas-disease/|website=Robert J. Kleberg, Jr. and Helen C. Kleberg Foundation|accessdate=8 September 2017|archiveurl=https://web.archive.org/web/20160728002936/http://www.klebergfoundation.org/texas-childrens-hospital-center-for-vaccine-development-awarded-grant-to-develop-therapeutic-vaccine-for-chagas-disease/|archivedate=28 July 2016|date=17 July 2015|deadurl=yes|df=}}
14. ^1 {{cite journal|last1=Gillespie|first1=Portia M.|last2=Beaumier|first2=Coreen M.|last3=Strych|first3=Ulrich|last4=Hayward|first4=Tara|last5=Hotez|first5=Peter J.|last6=Bottazzi|first6=Maria Elena|title=Status of vaccine research and development of vaccines for leishmaniasis|journal=Vaccine|date=3 June 2016|volume=34|issue=26|pages=2992–2995|doi=10.1016/j.vaccine.2015.12.071|pmid=26973063|issn=1873-2518}}
15. ^1 {{cite journal|last1=Asojo|first1=Oluwatoyin A.|last2=Kelleher|first2=Alan|last3=Liu|first3=Zhuyun|last4=Pollet|first4=Jeroen|last5=Hudspeth|first5=Elissa M.|last6=Rezende|first6=Wanderson C.|last7=Groen|first7=Mallory Jo|last8=Seid|first8=Christopher A.|last9=Abdeladhim|first9=Maha|last10=Townsend|first10=Shannon|last11=Castro|first11=Waldione de|last12=Mendes-Sousa|first12=Antonio|last13=Bartholomeu|first13=Daniella Castanheira|last14=Fujiwara|first14=Ricardo Toshio|last15=Bottazzi|first15=Maria Elena|last16=Hotez|first16=Peter J.|last17=Zhan|first17=Bin|last18=Oliveira|first18=Fabiano|last19=Kamhawi|first19=Shaden|last20=Valenzuela|first20=Jesus G.|title=Structure of SALO, a leishmaniasis vaccine candidate from the sand fly Lutzomyia longipalpis|journal=PLOS Neglected Tropical Diseases|date=9 March 2017|volume=11|issue=3|pages=e0005374|doi=10.1371/journal.pntd.0005374|url=http://journals.plos.org/plosntds/article?id=10.1371/journal.pntd.0005374|accessdate=8 September 2017|issn=1935-2735}}
16. ^1 {{cite journal|last1=Jiang|first1=Shibo|last2=Bottazzi|first2=Maria Elena|last3=Du|first3=Lanying|last4=Lustigman|first4=Sara|last5=Tseng|first5=Chien-Te Kent|last6=Curti|first6=Elena|last7=Jones|first7=Kathryn|last8=Zhan|first8=Bin|last9=Hotez|first9=Peter J|title=Roadmap to developing a recombinant coronavirus S protein receptor-binding domain vaccine for severe acute respiratory syndrome|journal=Expert Review of Vaccines|date=December 2012|volume=11|issue=12|pages=1405–1413|doi=10.1586/erv.12.126|pmc=3586247|issn=1476-0584}}
17. ^1 {{cite journal|last1=Chen|first1=Wen-Hsiang|last2=Du|first2=Lanying|last3=Chag|first3=Shivali M.|last4=Ma|first4=Cuiqing|last5=Tricoche|first5=Nancy|last6=Tao|first6=Xinrong|last7=Seid|first7=Christopher A.|last8=Hudspeth|first8=Elissa M.|last9=Lustigman|first9=Sara|last10=Tseng|first10=Chien-Te K.|last11=Bottazzi|first11=Maria Elena|last12=Hotez|first12=Peter J.|last13=Zhan|first13=Bin|last14=Jiang|first14=Shibo|title=Yeast-expressed recombinant protein of the receptor-binding domain in SARS-CoV spike protein with deglycosylated forms as a SARS vaccine candidate|journal=Human Vaccines & Immunotherapeutics|date=2014|volume=10|issue=3|pages=648–658|pmid=24355931|issn=2164-554X}}
18. ^1 {{cite journal|last1=Zhan|first1=Bin|last2=Beaumier|first2=Coreen M|last3=Briggs|first3=Neima|last4=Jones|first4=Kathryn M|last5=Keegan|first5=Brian P|last6=Bottazzi|first6=Maria Elena|last7=Hotez|first7=Peter J|title=Advancing a multivalent ‘Pan-anthelmintic’ vaccine against soil-transmitted nematode infections|journal=Expert Review of Vaccines|date=2014|volume=13|issue=3|pages=321–331|doi=10.1586/14760584.2014.872035|pmc=3934375|issn=1476-0584}}
19. ^1 {{cite web|title=Helminth Vaccine Discovery Program funded by Dr. Gary K. Michelson|url=https://michelsonmedical.org/2014/04/27/gary-michelson-funding-development-soil-transmitted-helminth-vaccine/|website=Michelson Medical Research Foundation|accessdate=8 September 2017|date=27 April 2014}}
20. ^1 {{cite web|title=The Global Network for Neglected Tropical Diseases|url=http://www.sabin.org/programs/global-network-neglected-tropical-diseases-0|website=Sabin|accessdate=9 September 2017|archiveurl=https://web.archive.org/web/20170906041445/http://www.sabin.org/programs/global-network-neglected-tropical-diseases-0|archivedate=6 September 2017|language=en}}
21. ^1 2 {{cite web|title=Onchocerciasis|url=http://www.sabin.org/programs/onchocerciasis|website=Sabin|accessdate=11 September 2017|archiveurl=https://web.archive.org/web/20170712124418/http://www.sabin.org/programs/onchocerciasis|archivedate=12 July 2017|language=en}}
22. ^1 {{cite journal|last1=Hotez|first1=Peter J.|last2=Bottazzi|first2=Maria Elena|last3=Zhan|first3=Bin|last4=Makepeace|first4=Benjamin L.|last5=Klei|first5=Thomas R.|last6=Abraham|first6=David|last7=Taylor|first7=David W.|last8=Lustigman|first8=Sara|title=The Onchocerciasis Vaccine for Africa—TOVA—Initiative|journal=PLOS Neglected Tropical Diseases|date=29 January 2015|volume=9|issue=1|pages=e0003422|doi=10.1371/journal.pntd.0003422|url=http://journals.plos.org/plosntds/article?id=10.1371/journal.pntd.0003422|accessdate=11 September 2017|issn=1935-2735}}
23. ^1 {{cite web|title=The Partners|url=http://www.riverblindnessvaccinetova.org/partners|website=The Onchocerciasis Vaccine for Africa Initiative|accessdate=11 September 2017|archiveurl=https://web.archive.org/web/20170214145404/http://www.riverblindnessvaccinetova.org/partners|archivedate=14 February 2017|language=en}}
24. ^1 {{cite web|title=The Onchocerciasis Vaccine for Africa (TOVA) - A global initiative to advance river blindness vaccine|url=http://www.eid.ed.ac.uk/eid/news/TOVA|website=Edinburgh Infectious Diseases|accessdate=11 September 2017|archiveurl=https://web.archive.org/web/20170911213348/http://www.eid.ed.ac.uk/eid/news/TOVA|archivedate=11 September 2017|date=27 August 2015}}
25. ^1 {{cite web|title=Coalition Against Typhoid|url=http://www.coalitionagainsttyphoid.org/|website=Coalition Against Typhoid|accessdate=14 September 2017|archiveurl=https://web.archive.org/web/20170914152813/http://www.coalitionagainsttyphoid.org/|archivedate=14 September 2017}}
26. ^1 {{cite journal|last1=Hotez|first1=Peter J|title=The Medical Biochemistry of Poverty and Neglect|journal=Molecular Medicine|date=16 December 2014|volume=20|issue=Suppl 1|pages=S31–S36|doi=10.2119/molmed.2014.00169|pmc=4374519|issn=1076-1551}}
27. ^1 {{cite web|title=Study of Co-administered Na-APR-1 (M74) and Na-GST-1 in Gabonese Children - Full Text View|url=https://clinicaltrials.gov/ct2/show/NCT02839161|website=clinicaltrials.gov|accessdate=18 September 2017|archiveurl=https://web.archive.org/web/20170918182441/https://clinicaltrials.gov/ct2/show/NCT02839161|archivedate=18 September 2017|language=en}}
28. ^1 {{cite web|title=A Phase I Study of the Safety, Reactogenicity, and Immunogenicity of Sm-TSP-2/Alhydrogel® With or Without GLA-AF for Intestinal Schistosomiasis in Healthy Adults - Full Text View|url=https://clinicaltrials.gov/ct2/show/study/NCT02337855|website=ClinicalTrials.gov|accessdate=18 September 2017|archiveurl=https://web.archive.org/web/20170918182703/https://clinicaltrials.gov/ct2/show/study/NCT02337855|archivedate=18 September 2017|language=en}}
29. ^1 {{cite web|title=A Phase Ib Study of the Safety, Reactogenicity, and Immunogenicity of Sm-TSP-2/Alhydrogel® With or Without AP 10-701 for Intestinal Schistosomiasis in Healthy Exposed Adults - Full Text View|url=https://clinicaltrials.gov/ct2/show/study/NCT03110757|website=ClinicalTrials.gov|accessdate=18 September 2017|archiveurl=https://web.archive.org/web/20170918182816/https://clinicaltrials.gov/ct2/show/study/NCT03110757|archivedate=18 September 2017|language=en}}
30. ^1 {{cite web|title=Chagas|url=http://www.sabin.org/programs/chagas|website=Sabin|accessdate=18 September 2017|archiveurl=https://web.archive.org/web/20170712113323/http://www.sabin.org/programs/chagas|archivedate=12 July 2017|language=en}}
31. ^1 {{cite web|title=Leishmaniasis|url=http://www.sabin.org/programs/leishmaniasis|website=Sabin|accessdate=18 September 2017|archiveurl=https://web.archive.org/web/20170712124326/http://www.sabin.org/programs/leishmaniasis|archivedate=12 July 2017|language=en}}
32. ^1 {{cite web|title=SARS/MERS|url=http://www.sabin.org/programs/sarsmers|website=Sabin|accessdate=18 September 2017|archiveurl=https://web.archive.org/web/20170712124505/http://www.sabin.org/programs/sarsmers|archivedate=12 July 2017|language=en}}
33. ^1 {{cite web|title=Sabin Vaccine Colloquium|url=https://www.gatesfoundation.org/Media-Center/Press-Releases/2000/05/Sabin-Vaccine-Colloquium|website=Bill & Melinda Gates Foundation|accessdate=20 September 2017|archiveurl=https://web.archive.org/web/20150920193811/http://www.gatesfoundation.org/Media-Center/Press-Releases/2000/05/Sabin-Vaccine-Colloquium|archivedate=20 September 2015|language=en}}
34. ^1 {{cite web|title=The Albert B. Sabin Gold Medal Award|url=http://www.sabin.org/sabin-gold-medal-award|website=Sabin|accessdate=21 September 2017|archiveurl=https://web.archive.org/web/20170828062928/http://www.sabin.org/sabin-gold-medal-award|archivedate=28 August 2017|language=en}}
35. ^1 {{cite web|author1=Dipali Pathak|title=Grant to develop chikungunya virus vaccine awarded|url=https://www.bcm.edu/news/grants/grant-chikungunya-virus-vaccine|website=Baylor College of Medicine|accessdate=3 October 2017|archiveurl=https://web.archive.org/web/20170520080133/https://www.bcm.edu/news/grants/grant-chikungunya-virus-vaccine|archivedate=20 May 2017|language=en|date=30 August 2016}}
36. ^1 {{cite web|title=The Albert B. Sabin Gold Medal Award|url=http://www.sabin.org/sabin-gold-medal-award|website=Sabin|accessdate=4 October 2017|archiveurl=https://web.archive.org/web/20170828062928/http://www.sabin.org/sabin-gold-medal-award|archivedate=28 August 2017|language=en}}
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}}

External links

  • {{URL|https://www.facebook.com/sabinvaccine/|Sabin Vaccine Institute on Facebook}}
  • {{URL|https://twitter.com/sabinvaccine|Sabin Vaccine Institute on Twitter}}

8 : 1993 establishments in Washington, D.C.|Advocacy groups in the United States|Charities based in the United States|Institutes based in the United States|Medical and health organizations based in Washington, D.C.|Non-profit organizations based in Washington, D.C.|Scientific organizations established in 1993|Vaccination-related organizations
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