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词条 Santa Cruz Biotechnology
释义

  1. History

  2. References

Santa Cruz Biotechnology is a developer of biological products for medical research,[1][2] and is one of the world’s largest suppliers of antibodies.[3] The company was founded in 1991 by Dr. John Stephenson and his wife Brenda Stephenson in Santa Cruz, California.[4] Santa Cruz Biotechnology headquarters are located in Dallas, Texas, with additional US facilities in Paso Robles, California,[5] and Sun Valley, Idaho. The company also has international locations in Germany, Shanghai and Canada.[6]

History

The company was originally headquartered in Santa Cruz, California, and began offering antibodies to the research community.[7] Other products lines were added over the years – siRNAs in 2007,[8] shRNAs in 2009,[9] and laboratory supplies in 2010.

In 2010, the offering of biochemical was expanded from just a few hundred to over 100,000 different products.[10] Products related to CRISPR were introduced in 2015[11] for over 37,000 mouse and human genes.

Santa Cruz Biotechnology has had issues with the USDA for a number of years due to allegations of Animal Welfare Act violations. In May 2016, the company settled with the USDA, paying a $3.5 million fine for its alleged violations and agreed to the revocation of its polyclonal antibody dealer license effective from December 31, 2016.[12][13]

References

1. ^{{cite web|url=http://www.santacruzsentinel.com/article/ZZ/20081211/NEWS/812119851|title=Santa Cruz Biotechnology opens office in Idaho|publisher=}}
2. ^{{cite web|url=https://www.bloomberg.com/research/stocks/private/snapshot.asp?privcapId=50230932|title=Santa Cruz Biotechnology, Inc.: Private Company Information - Bloomberg|publisher=}}
3. ^{{cite web|url=http://www.sanluisobispo.com/news/business/article39464694.html|title=Economic growth pushes SLO County higher in national ranking|publisher=}}
4. ^{{cite web|url=http://archives.mtexpress.com/index2.php?ID=2005123867#.WA6AbvkrJhE|title=Idaho Mountain Express: Biotechnology firm sets up shop in Ketchum - December 3, 2008|publisher=}}
5. ^{{cite web|url=http://www.pasoroblespress.com/v2_news_articles.php?heading=0&page=72&story_id=7604|title=Paso Robles Press Santa Cruz Biotech breaks ground on new building|publisher=}}
6. ^{{cite web|url=http://www.abc6.com/story/33493407/santa-cruz-biotechnology-opens-new-office-in-canada|title=Santa Cruz Biotechnology Opens New Office in Canada|publisher=}}
7. ^{{cite journal |pmc=238044|year=1993|author1=Jeang|first1=K. T.|title=In vitro and in vivo binding of human immunodeficiency virus type 1 Tat protein and Sp1 transcription factor|journal=Journal of Virology|volume=67|issue=10|pages=6224–6233|last2=Chun|first2=R|last3=Lin|first3=N. H.|last4=Gatignol|first4=A|last5=Glabe|first5=C. G.|last6=Fan|first6=H}}
8. ^{{cite journal|title=Adiponectin modulates inflammatory reactions via calreticulin receptor–dependent clearance of early apoptotic bodies|first1=Yukihiro|last1=Takemura|first2=Noriyuki|last2=Ouchi|first3=Rei|last3=Shibata|first4=Tamar|last4=Aprahamian|first5=Michael T.|last5=Kirber|first6=Ross S.|last6=Summer|first7=Shinji|last7=Kihara|first8=Kenneth|last8=Walsh|date=1 February 2007|publisher=|journal=J Clin Invest|volume=117|issue=2|pages=375–386|doi=10.1172/JCI29709|pmid=17256056|pmc=1770947}}
9. ^{{cite journal|url=http://ajpcell.physiology.org/content/296/4/C711|title=Embryonic stem cell differentiation into smooth muscle cells is mediated by Nox4-produced H2O2|journal=American Journal of Physiology. Cell Physiology|first1=Qingzhong|last1=Xiao|first2=Zhenling|last2=Luo|first3=Anna Elena|last3=Pepe|first4=Andriani|last4=Margariti|first5=Lingfang|last5=Zeng|first6=Qingbo|last6=Xu|date=1 April 2009|publisher=|volume=296|issue=4|pages=C711–C723|via=ajpcell.physiology.org|doi=10.1152/ajpcell.00442.2008|pmid=19036941}}
10. ^{{cite journal|title=EIF2A-dependent translational arrest protects leukemia cells from the energetic stress induced by NAMPT inhibition|first1=Chiara|last1=Zucal|first2=Vito G.|last2=D’Agostino|first3=Antonio|last3=Casini|first4=Barbara|last4=Mantelli|first5=Natthakan|last5=Thongon|first6=Debora|last6=Soncini|first7=Irene|last7=Caffa|first8=Michele|last8=Cea|first9=Alberto|last9=Ballestrero|first10=Alessandro|last10=Quattrone|first11=Stefano|last11=Indraccolo|first12=Alessio|last12=Nencioni|first13=Alessandro|last13=Provenzani|date=5 November 2015|publisher=|journal=BMC Cancer|volume=15|pages=855|doi=10.1186/s12885-015-1845-1|pmid=26542945|pmc=4636066}}
11. ^{{cite journal|title=The mannose receptor LY75 (DEC205/CD205) modulates cellular phenotype and metastatic potential of ovarian cancer cells|first1=Adnen|last1=Faddaoui|first2=Magdalena|last2=Bachvarova|first3=Marie|last3=Plante|first4=Jean|last4=Gregoire|first5=Marie-Claude|last5=Renaud|first6=Alexandra|last6=Sebastianelli|first7=Stephane|last7=Gobeil|first8=Chantale|last8=Morin|first9=Elizabeth|last9=Macdonald|first10=Barbara|last10=Vanderhyden|first11=Dimcho|last11=Bachvarov|date=9 February 2016|publisher=|journal=Oncotarget|volume=7|issue=12|pages=14125–14142|doi=10.18632/oncotarget.7288|pmid=26871602|pmc=4924702}}
12. ^{{cite web|url=https://speakingofresearch.com/2016/06/16/santa-cruz-biotechnology-and-the-usda/|title=Santa Cruz Biotechnology and the USDA|first=|last=Editor|date=16 June 2016|publisher=}}
13. ^{{cite journal|url=http://www.nature.com/news/us-government-issues-historic-3-5-million-fine-over-animal-welfare-1.19958|title=US government issues historic $3.5-million fine over animal welfare|journal=Nature|first=Sara|last=Reardon|publisher=|doi=10.1038/nature.2016.19958|year=2016}}

2 : Biotechnology companies established in 1991|Companies based in Dallas
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