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词条 Signal-regulatory protein
释义

  1. References

{{Pfam_box
| Symbol = SRP
| Name = Signal-regulatory protein
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| Membranome family= 42
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A Signal-regulatory protein (SIRP) is one of a family of transmembrane glycoproteins involved in immunological signalling, expressed mainly by myeloid cells.[1][2]

Members include :

  • Signal-regulatory protein alpha, ligand=CD47[1]
  • SIRPB1
  • SIRPD
  • SIRPG, ligand=CD47[1]

References

1. ^{{cite journal | vauthors = van Beek EM, Cochrane F, Barclay AN, van den Berg TK | title = Signal regulatory proteins in the immune system | journal = Journal of Immunology | volume = 175 | issue = 12 | pages = 7781–7 | date = December 2005 | pmid = 16339510 | doi = 10.4049/jimmunol.175.12.7781 }}
2. ^{{cite journal | vauthors = Barclay AN, Brown MH | title = The SIRP family of receptors and immune regulation | journal = Nature Reviews. Immunology | volume = 6 | issue = 6 | pages = 457–64 | date = June 2006 | pmid = 16691243 | doi = 10.1038/nri1859 }}
{{membrane-protein-stub}}

1 : Single-pass transmembrane proteins

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