“Sirius Red”的意思、由来-开放百科全书

词条

Sirius Red

释义

References

{{Chembox
| ImageFile = Sirius Red F 3B.svg
| ImageSize = 300px
| ImageAlt =
| IUPACName = Hexasodium (3E)-4-oxo-7-[[(6E)-5-oxo-7-sulfonato-6-[[2-sulfonato-4-[(4-sulfonatophenyl)diazenyl]phenyl]hydrazinylidene]naphthalen-2-yl]carbamoylamino]-3-[[2-sulfonato-4-[(4-sulfonatophenyl)diazenyl]phenyl]hydrazinylidene]naphthalene-2-sulfonate
| OtherNames = Direct Red 80; Picrosirius Red
| Section1 = {{Chembox Identifiers
| CASNo = 2610-10-8
| PubChem = 9571131
| SMILES = C1=CC(=CC=C1N=NC2=CC(=C(C=C2)N/N=C/3\\C(=O)C4=C(C=C3S(=O)(=O)[O-])C=C(C=C4)NC(=O)NC5=CC6=C(C(=O)/C(=N\C7=C(C=C(C=C7)N=NC8=CC=C(C=C8)S(=O)(=O)[O-])S(=O)(=O)[O-])/C(=C6)S(=O)(=O)[O-])C=C5)S(=O)(=O)[O-])S(=O)(=O)[O-].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+]
| Section2 = {{Chembox Properties
| C=45|H=26|N=10|Na=6|O=21|S=6
| Appearance =
| Density =
| MeltingPt =
| BoilingPt =
| Solubility =
| Section3 = {{Chembox Hazards
| MainHazards =
| FlashPt =
| AutoignitionPt =
}}Sirius Red F 3B (Direct Red 80) is a azo dye used principally in staining methods for collagen and amyloid with the molecular formula C₄₅H₂₆N₁₀Na₆O₂₁S₆.^[1]

In histology, sirius red staining is used in various domains of diagnostic to observe fibrosis levels in a lot of cases of inflammation induced by cancer, vascular or metabolic pathologies.^[2]

In bright field microscopy the following can be observed:

The nuclei in yellow
The cytoplasm in yellow
Collagen fibers in red
Muscular fibers in yellow
Red blood cells in yellow

References

1. ^ResearchGate{{cite web |url=https://www.researchgate.net/publication/50591278_Certification_procedures_for_sirius_red_F3B_%28CI_35780_Direct_red_80%29 |title=Certification procedures for sirius red F3B |accessdate=2015-08-21}}
2. ^Sirius red

2 : Staining dyes|Azo dyes

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