| 词条 | Solid phase sequencing |
| 释义 |
The principle of solid phase DNA sequencing was described in 1989 based on binding of biotinylated DNA to streptavidin coated magnetic beads and elution of one DNA strands selectively using alkali [1]. The method allowed robotic applications suitable for clinical sequencing, but the magnetic handling has also found frequent use in many molecular applications, including sample handling for DNA diagnostics [2]. The use of solid phase methods for DNA handling is now frequently used as an integrated part of many of the next generation DNA sequencing methods, as well as numerous molecular diagnostics applications. References 2 : DNA sequencing|Biotechnology |
| 随便看 |
|
开放百科全书收录14589846条英语、德语、日语等多语种百科知识，基本涵盖了大多数领域的百科知识，是一部内容自由、开放的电子版国际百科全书。