| 词条 | T-1123 |
| 释义 |
| Name = T-1123 | OtherNames = AR-16, TL-1217, TL-1299 | ImageFile = T-1123.png | IUPACName = N,N-diethyl-N-methyl-3-[(methylcarbamoyl)oxy]anilinium chloride | SystematicName = | Section1 = {{Chembox Identifiers | ChemSpiderID = 42375 | PubChem = 46574 | CASNo = 64046-12-4 | StdInChI=1S/C13H20N2O2.ClH/c1-5-15(4,6-2)11-8-7-9-12(10-11)17-13(16)14-3;/h7-10H,5-6H2,1-4H3;1H | StdInChIKey=JLNMGRFEXZJGFZ-UHFFFAOYSA-N | SMILES = CC[N+](C)(CC)c1cccc(c1)OC(=O)NC.[Cl-] }} | Section2 = {{Chembox Properties | C = 13 | H =21 | N = 2 | O = 2 |Cl=1 }} | Section3 = {{Chembox Related | OtherCompounds = Neostigmine Miotine }} | Section4 = | Section5 = | Section6 = }} T-1123 is a carbamate-based acetylcholinesterase inhibitor. It was investigated as a chemical warfare agent starting in 1940. It does not go through the blood-brain barrier due to the charge on quaternary nitrogen. The antidote is atropine.[1] T-1123 is a quaternary ammonium ion. A phenyl carbamate ester is bonded in the meta position to the nitrogen on a diethylmethyl amine. See also
References1. ^{{cite book|last1=Gupta|first1=Ramesh C.|title=Handbook of Toxicology of Chemical Warfare Agents|date=2015|publisher=Academic Press|isbn=9780128004944|pages=338–339|url=https://books.google.com.au/books?id=MXKDBAAAQBAJ&pg=PA338|language=en}} Extra reading
5 : Carbamate nerve agents|Quaternary ammonium compounds|Phenol esters|Acetylcholinesterase inhibitors|Chemical weapons |
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