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词条 Takeshi Hirayama
释义

  1. Early life and education

  2. Career

  3. Research

     Secondhand smoke  Diet and cancer 

  4. Honors and awards

  5. Personal life

  6. References

{{Nihongo|Takeshi Hirayama|平山 雄|Hirayama Takeshi|extra=January 1, 1923 – October 26, 1995}} was a Japanese cancer epidemiologist and anti-tobacco activist who served as the chief of the epidemiology division at the {{Ill|National Cancer Center|ja|国立がん研究センター}} in Tokyo from 1965 until 1985. He has been credited with publishing the first study linking passive smoking to lung cancer, and also conducted research on the relationship between certain dietary factors and cancer.

Early life and education

Hirayama was born on January 1, 1923, in Kyoto, Japan.[1] When he was three, his father, Tohshi Hirayama, became professor of surgery at Manchuria Medical College, which led to him and his family moving to the city of Harbin in China.[2] Hirayama graduated from Manchuria Medical College in 1945, and received a degree in medical science from Kyoto University in 1951 and a Master of Public Health degree from Johns Hopkins University in 1952.[1]

Career

In 1946, Hirayama moved to Tokyo, where he took a job at the Japanese National Institute of Hygiene.[2] In 1959, he moved to New York City to study the association between tobacco smoking and lung cancer at Memorial Sloan Kettering Cancer Center.[2] In 1965, he was appointed the chief of the epidemiology division at the National Cancer Institute (also known as the National Cancer Centre) in Tokyo.[2] He remained in this position until 1985.[1] Soon afterward, he designed a large cohort study of over 260,000 subjects, known as the "six prefecture" cohort study, which he continued to follow up until he retired.[2] During his career, he became a prominent figure in the anti-smoking movement, and supported many anti-smoking activities by non-governmental organizations.[2]

Research

Secondhand smoke

In 1981, Hirayama published a study of 265,000 people which found an association between exposure to secondhand smoke and an increased risk of lung cancer.[3][4][5] This study has been described as "one of the most frequently cited studies in regulatory proceedings, risk assessments, and the media" with regard to secondhand smoke.[13] It has also been described as the first study linking secondhand smoke to lung cancer in nonsmokers,[6] although two other studies were published around the same time with similar findings.[7] In response to the study, the tobacco industry decided to produce a study of their own, dubbed the "Japanese spousal study", with the aim of refuting Hirayama's findings.[8] In addition, the Tobacco Institute responded to Hirayama's 1981 study by writing a letter to his superior criticizing the study.[6] In 1984, Hirayama published a cohort study of 265,118 adults which reached conclusions similar to those of his 1981 study, namely, that non-smoking wives of smoking husbands were at an increased risk of lung cancer and ischemic heart disease.[9][10]

Diet and cancer

Hirayama also studied the relationship between green and yellow vegetable consumption and a decreased risk of certain cancers.[1][2][10] He also published a number of studies linking increased consumption of meat, eggs, butter, and cheese to an increased risk of breast cancer.[11]

Honors and awards

In 1988 and 1993, Hirayama received the WHO commemorative medal on tobacco or health.[2] In 1989, he received the Ramazzini Award from the Collegium Ramazzini "for his contributions to the knowledge of the role of lifestyle in the genesis of cancer".[12]

Personal life

Hirayama's hobbies included painting and sketching.[2] He died on October 26, 1995.[1] He was survived by his wife, Yukiko, and their two sons.[2]

References

1. ^{{cite journal|last1=Wynder|first1=Ernst L.|title={{sic|In Memo|rium|hide=y|expected=In Memoriam}}|journal=Nutrition and Cancer|date=January 1996|volume=25|issue=2|pages=218–218|doi=10.1080/01635589609514444}}
2. ^{{cite journal | url=http://europepmc.org/backend/ptpmcrender.fcgi?accid=PMC2551293&blobtype=pdf | title=Obituaries | journal=BMJ |date=November 1995 | volume=311 | pages=1429 | PMC=2551293}}
3. ^{{cite journal|last1=Hirayama|first1=T|title=Non-smoking wives of heavy smokers have a higher risk of lung cancer: a study from Japan.|journal=British Medical Journal (Clinical research ed.)|date=17 January 1981|volume=282|issue=6259|pages=183–5|pmid=6779940|doi=10.1136/bmj.282.6259.183|pmc=1503989}}
4. ^{{cite web | url=https://www.nytimes.com/1981/01/16/us/cancer-study-reports-high-risk-for-wives-of-smoking-husbands.html | title=Cancer Study Reports High Risk for Wives of Smoking Husbands | work=The New York Times | date=16 January 1981 | accessdate=19 August 2015 | author=Altman, Lawrence K.}}
5. ^{{Cite web |url=http://content.time.com/time/magazine/article/0,9171,922606,00.html |title=Medicine: Tobacco Wars |website=Time |publication-date=6 July 1981 |access-date=25 March 2017}}
6. ^{{cite book | url=https://books.google.com/books?id=VZ1axrolCpkC | title=Rescuing Science from Politics: Regulation and the Distortion of Scientific Research | publisher=Cambridge University Press | author=Steinzor, Rena | year=2006 | pages=30}}
7. ^{{cite journal|last1=Ong|first1=E|last2=Glantz|first2=SA|title=Hirayama's work has stood the test of time.|journal=Bulletin of the World Health Organization|year=2000|volume=78|issue=7|pages=938–9|pmid=10994268|url=http://apps.who.int/iris/bitstream/10665/57635/1/classics.pdf?ua=1|pmc=2560803}}
8. ^{{cite journal|last1=Hong|first1=M.-K.|title=How the tobacco industry responded to an influential study of the health effects of secondhand smoke|journal=BMJ|date=14 December 2002|volume=325|issue=7377|pages=1413–1416|doi=10.1136/bmj.325.7377.1413|pmc=1124865|pmid=12480862}}
9. ^{{cite book | url=https://books.google.com/books/about/Lung_Cancer.html?id=qgMZnQAACAAJ | title=Lung Cancer: Causes and Prevention | publisher=Verlag Chemie International | author=Hirayama, Takeshi | year=1984 | pages=175–95 }}
10. ^{{cite journal | url=https://books.google.com/books?id=wVBOlTz4-ycC&pg=PA42 | title=Friendship is a good health guide | journal=New Scientist |date=March 1985 | volume=105 | issue=1448 | pages=42–44}}
11. ^{{cite book | url=https://books.google.com/books?id=PnO7_2F12p0C&pg=PA264 | title=Diet for a New America | publisher=HJ Kramer | author=Robbins, John | year=1987 | pages=264}}
12. ^{{cite web | url=http://www.collegiumramazzini.org/ramazziniaward.asp | title=Ramazzini Award | publisher=Collegium Ramazzini | accessdate=19 August 2015}}
{{Authority control}}{{DEFAULTSORT:Hirayama, Takeshi}}

9 : 1923 births|1995 deaths|People from Kyoto|Kyoto University alumni|Johns Hopkins University alumni|Anti-smoking activists|Cancer epidemiologists|20th-century Japanese scientists|Japanese health activists

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