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词条 Tanshinone
释义

  1. References

  2. External links

Tanshinones are a class of chemical compounds. Examples include dihydrotanshinone, tanshinone I, or tanshinone IIA. These compounds are all naturally occurring and can all be isolated from Salvia miltiorrhiza.[1][2]

Dihydrotanshinone I has been reported to have cytotoxicity to a variety of tumor cells.[3]

Tanshinone I is anti-inflammatory, and modulates or prevents breast cancer metastasis by regulating adhesion molecules.[4]

Tanshinone IIA is anti-inflammatory, an antioxidant, and cytotoxic against a variety of cell lines.[5]

References

1. ^{{cite journal |vauthors=Lee WY, Cheung CC, Liu KW, etal |title=Cytotoxic effects of tanshinones from Salvia miltiorrhiza on doxorubicin-resistant human liver cancer cells |journal=J. Nat. Prod. |volume=73 |issue=5 |pages=854–9 |date=May 2010 |pmid=20455578 |doi=10.1021/np900792p}}
2. ^{{cite journal |author1=Yoon Y |author2=Kim YO |author3=Jeon WK |author4=Park HJ |author5=Sung HJ |title=Tanshinone IIA isolated from Salvia miltiorrhiza BUNGE induced apoptosis in HL60 human premyelocytic leukemia cell line |journal=J Ethnopharmacol |volume=68 |issue=1–3 |pages=121–7 |date=December 1999 |pmid=10624871 |doi=10.1016/S0378-8741(99)00059-8}}
3. ^{{cite journal | doi = 10.1111/j.1745-7270.2008.00370.x| pmid = 18180848| title = Dihydrotanshinone I inhibits angiogenesis both in vitro and in vivo| journal = Acta Biochimica et Biophysica Sinica| volume = 40| issue = 1| pages = 1–6| year = 2008| last1 = Bian| first1 = W| last2 = Chen| first2 = F| last3 = Bai| first3 = L| last4 = Zhang| first4 = P| last5 = Qin| first5 = W}}
4. ^{{cite web|url=https://www.sigmaaldrich.com/catalog/product/sigma/t5330|title=Tanshinone I T5330|website=Sigma-Aldrich}}
5. ^{{cite web|url=https://www.sigmaaldrich.com/catalog/product/sigma/t4952|title=Tanshinone IIA T4952|website=Sigma-Aldrich}}

External links

  • {{commons category inline|tanshinones}}

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