| 释义 |
- References
- Further reading
{{Orphan|date=October 2018}}{{Infobox_gene}}Tau tubulin kinase 1 is a protein that in humans is encoded by the TTBK1 gene. [1] References 1. ^{{cite web| title = Entrez Gene: Tau tubulin kinase 1| url = https://www.ncbi.nlm.nih.gov/gene/84630| accessdate = 2017-03-23}}
Further reading {{refbegin | 2}}- {{cite journal |vauthors=Sato S, Xu J, Okuyama S, Martinez LB, Walsh SM, Jacobsen MT, Swan RJ, Schlautman JD, Ciborowski P, Ikezu T |title=Spatial learning impairment, enhanced CDK5/p35 activity, and downregulation of NMDA receptor expression in transgenic mice expressing tau-tubulin kinase 1 |journal=J. Neurosci. |volume=28 |issue=53 |pages=14511–21 |year=2008 |pmid=19118186 |doi=10.1523/JNEUROSCI.3417-08.2008 |url=}}
- {{cite journal |vauthors=Vázquez-Higuera JL, Martínez-García A, Sánchez-Juan P, Rodríguez-Rodríguez E, Mateo I, Pozueta A, Frank A, Valdivieso F, Berciano J, Bullido MJ, Combarros O |title=Genetic variations in tau-tubulin kinase-1 are linked to Alzheimer's disease in a Spanish case-control cohort |journal=Neurobiol. Aging |volume=32 |issue=3 |pages=550.e5–9 |year=2011 |pmid=20096481 |doi=10.1016/j.neurobiolaging.2009.12.021 |url=}}
- {{cite journal |vauthors=Vázquez-Higuera JL, Martínez-García A, Sánchez-Juan P, Rodríguez-Rodríguez E, Mateo I, Pozueta A, Frank A, Valdivieso F, Berciano J, Bullido MJ, Combarros O |title=Genetic variations in tau-tubulin kinase-1 are linked to Alzheimer's disease in a Spanish case-control cohort |journal=Neurobiol. Aging |volume=32 |issue=3 |pages=550.e5–9 |year=2011 |pmid=20096481 |doi=10.1016/j.neurobiolaging.2009.12.021 |url=}}
- {{cite journal |vauthors=Yu NN, Yu JT, Xiao JT, Zhang HW, Lu RC, Jiang H, Xing ZH, Tan L |title=Tau-tubulin kinase-1 gene variants are associated with Alzheimer's disease in Han Chinese |journal=Neurosci. Lett. |volume=491 |issue=1 |pages=83–6 |year=2011 |pmid=21219968 |doi=10.1016/j.neulet.2011.01.011 |url=}}
- {{cite journal |vauthors=Lund H, Cowburn RF, Gustafsson E, Strömberg K, Svensson A, Dahllund L, Malinowsky D, Sunnemark D |title=Tau-tubulin kinase 1 expression, phosphorylation and co-localization with phospho-Ser422 tau in the Alzheimer's disease brain |journal=Brain Pathol. |volume=23 |issue=4 |pages=378–89 |year=2013 |pmid=23088643 |doi=10.1111/bpa.12001 |url=}}
- {{cite journal |vauthors=Kiefer SE, Chang CJ, Kimura SR, Gao M, Xie D, Zhang Y, Zhang G, Gill MB, Mastalerz H, Thompson LA, Cacace AM, Sheriff S |title=The structure of human tau-tubulin kinase 1 both in the apo form and in complex with an inhibitor |journal=Acta Crystallogr F |volume=70 |issue=Pt 2 |pages=173–81 |year=2014 |pmid=24637750 |pmc=3936456 |doi=10.1107/S2053230X14000144 |url=}}
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