| 词条 | Amdoparvovirus | ||||||||||||||||||||||||||||
| 释义 |
| image = | image_alt = | image_caption = | taxon = Amdoparvovirus | authority = | synonyms = | synonyms_ref = | type_species = Carnivore amdoparvovirus 1 | subdivision_ranks = Species | subdivision =
}}Amdoparvovirus is a genus of viruses, in the family Parvoviridae,[1][2] in the subfamily Parvovirinae. Mustelids (minks, ferrets, and foxes), skunk, and raccoons serve as natural hosts. There are currently four species in this genus including the type species Carnivore amdoparvovirus 1 (Aleutian mink disease virus).[3] Diseases associated with this genus include: progressive disorder of immune system.[4][5][6][7][8] TaxonomyGroup: ssDNA{{Collapsible list|title= Order: Unassigned|1={{Collapsible list| framestyle=border:none; padding:1.0em;|title=Family: Parvoviridae |1={{Collapsible list| framestyle=border:none; padding:1.0em;|title=Sub-Family: Parvovirinae |1={{hidden begin|title=Genus: Amdoparvovirus}}
}} }} }}[2] StructureViruses in genus Amdoparvovirus have non-enveloped protein particles with T=1 icosahedral symmetry. [2] They are around 18-26 nm in diameter and contain a single linear single-stranded DNA genome of around 4.8kb in length. [4]
Life cycleViral replication is nuclear. Entry into the host cell is achieved by attachment to host receptors, which mediate clathrin-mediated endocytosis. Replication follows the rolling-hairpin model.[2] DNA templated transcription, with some alternative splicing mechanism is the method of transcription. The virus may exit the host cell by vesicular trafficking following nuclear pore export or be released following cell lysis. Mustelids, skunk, and raccoons serve as the natural host. Transmission routes are oral and respiratory. [4]
References1. ^{{cite journal | last1 = Cotmore | first1 = SF | last2 = Agbandje-McKenna | first2 = M | last3 = Canuti | first3 = M | last4 = Chiorini | first4 = JA | last5 = Eis-Hubinger | first5 = A | last6 = Hughes | first6 = J | last7 = Mietzsch | first7 = M | last8 = Modha | first8 = S | last9 = Ogliastro | first9 = M | last10 = Pénzes | first10 = JJ | last11 = Pintel | first11 = DJ | last12 = Qiu | first12 = J | last13 = Soderlund-Venermo | first13 = M | last14 = Tattersall | first14 = P | last15 = Tijssen | first15 = P | last16 = and the ICTV Report Consortium | year = 2019 | title = ICTV Virus Taxonomy Profile: Parvoviridae | journal = Journal of General Virology | volume = 100 | issue = 3 | pages = 367–368 | doi = 10.1099/jgv.0.001212| pmid = 30672729}} 2. ^1 2 3 {{cite web |title=ICTV 10th Report (2018) |url=https://talk.ictvonline.org/ictv-reports/ictv_online_report/ssdna-viruses/w/parvoviridae }} 3. ^{{cite web |title=ICTV 10th Report (2018)Amdoparvovirus |url=https://talk.ictvonline.org/ictv-reports/ictv_online_report/ssdna-viruses/w/parvoviridae/1039 }} 4. ^1 2 {{cite web|title=Viral Zone|url=http://viralzone.expasy.org/all_by_species/566.html|publisher=ExPASy|accessdate=12 June 2015}} 5. ^{{cite web|last1=ICTV|title=Virus Taxonomy: 2017 Release|url=https://talk.ictvonline.org/files/master-species-lists/m/msl/7185|accessdate=16 August 2018}} 6. ^{{Cite journal | last1 = Cheng | first1 = F. | last2 = Chen | first2 = A. Y. | last3 = Best | first3 = S. M. | last4 = Bloom | first4 = M. E. | last5 = Pintel | first5 = D. | last6 = Qiu | first6 = J. | doi = 10.1128/JVI.01917-09 | title = The Capsid Proteins of Aleutian Mink Disease Virus Activate Caspases and Are Specifically Cleaved during Infection | journal = Journal of Virology | volume = 84 | issue = 6 | pages = 2687–2696 | year = 2009 | pmid = 20042496 | pmc =2826067 }} 7. ^{{Cite journal | last1 = Li | first1 = L. | last2 = Pesavento | first2 = P. A. | last3 = Woods | first3 = L. | last4 = Clifford | first4 = D. L. | last5 = Luff | first5 = J. | last6 = Wang | first6 = C. | last7 = Delwart | first7 = E. | doi = 10.3201/eid1710.110233 | title = Novel Amdovirus in Gray Foxes | journal = Emerging Infectious Diseases | volume = 17 | issue = 10 | pages = 1876–1878 | year = 2011 | pmid = 22000359 | pmc =3310670 }} 8. ^{{Cite journal|title = Amdoparvoviruses in small mammals: expanding our understanding of parvovirus diversity, distribution, and pathology|journal = Virology|volume = 6|date = 2015-01-01|pages = 1119|doi = 10.3389/fmicb.2015.01119|pmid = 26528267|pmc = 4600916|first = Marta|last = Canuti|first2 = Hugh G.|last2 = Whitney|first3 = Andrew S.|last3 = Lang}} External links
2 : Parvovirinae|Parvoviruses |
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