The Nook may refer to:

• The Nook, Shropshire, a United Kingdom location
• The Nook, Isle of Man, an element of race courses
• The Nook (Spring Garden Township, Pennsylvania), a historic home

• Topographic isolation
• Topographic map (neuroanatomy)
• Topographic mapping
• Topographic poem
• Topographic Relations of Philip II
• Topographic surveying and mapping
• Topography as the study of place
• Topography (disambiguation)
• Topography of Mars
• Topography of Phitsanulok Province
• Topography of Romania
• Topography of Terror
• Topography of the Lungs
• Topography of the Moon
• Topoisomerase I
• Topoisomerase II
• Topoisomerase inhibitor
• Topoisomerases
• Topola
• Topola Municipality
• Topolanek
• Topolany, Czech Republic
• Topolchane, Sliven Province
• Topolcianky
• Topolice