| 词条 | Thiadiazoles |
| 释义 |
In chemistry thiadiazoles are a sub-family of azole compounds. Structurally they are five-membered heterocyclic compounds containing two nitrogen and a sulfur atoms, and two double bonds, to give an aromatic ring; with the name thiadiazole originating from the Hantzsch–Widman nomenclature. Four possible structures exist depending on the relative positions of the heteroatoms; these forms do not interconvert and hence are structural isomers and not tautomers. The compounds themselves are rarely synthesized and possess no particular application, however compounds bearing them as a structural motif are fairly common in pharmacology.[1][2][3] References1. ^{{cite journal|last1=Hu|first1=Yang|last2=Li|first2=Cui-Yun|last3=Wang|first3=Xiao-Ming|last4=Yang|first4=Yong-Hua|last5=Zhu|first5=Hai-Liang|title=1,3,4-Thiadiazole: Synthesis, Reactions, and Applications in Medicinal, Agricultural, and Materials Chemistry|journal=Chemical Reviews|volume=114|issue=10|year=2014|pages=5572–5610|issn=0009-2665|doi=10.1021/cr400131u|pmid=24716666}} 2. ^{{cite journal|last1=Jain|first1=Abhishek Kumar|last2=Sharma|first2=Simant|last3=Vaidya|first3=Ankur|last4=Ravichandran|first4=Veerasamy|last5=Agrawal|first5=Ram Kishore|title=1,3,4-Thiadiazole and its Derivatives: A Review on Recent Progress in Biological Activities|journal=Chemical Biology & Drug Design|volume=81|issue=5|year=2013|pages=557–576|issn=1747-0277|doi=10.1111/cbdd.12125}} {{open access}} 3. ^{{cite book|author1=Wim Dehaen|author2=Vasiliy A. Bakulev|author3=Edward C. Taylor|author4=Jonathan A. Ellman|title=The Chemistry of Heterocyclic Compounds, The Chemistry of 1,2,3-Thiadiazoles|url=https://books.google.com/books?id=-XMt2cdjIfAC&pg=PR5|date=27 April 2004|publisher=John Wiley & Sons|isbn=978-0-471-65691-3|pages=5–}} 2 : Thiadiazoles|Functional groups |
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