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Thicknesse is an English surname. Notable people with the surname include: - Cuthbert Thicknesse (1887–1971), Dean of St Albans
- Francis Thicknesse (1829–1921), Bishop suffragan of Leicester
- George Thicknesse, 19th Baron Audley (1758–1818), English peer
- Norman Thicknesse (1858–1946), Archdeacon of Middlesex
- Philip Thicknesse (1719–1792), English writer
- Ralph Anthony Thicknesse (1800–1854), British politician
- Viv Thicknesse (1910–1986), Australian rugby league and rugby union player
{{surname}} 1 : English-language surnames |