This Changes Everything may refer to:

• This Changes Everything (book), a book on climate change by Naomi Klein,
• This Changes Everything (2015 film), a film by Avi Lewis based on the book,
• This Changes Everything (2018 film), a film on sexism in Hollywood by Tom Donahue.
• This Changes Everything (album)

• A guide to the arrangement of British insects
• A Guide to the Astral Plane
• A Guide to the New Ruins of Great Britain
• A Guide to the Old Buildings of the Cape
• A Guide to the Project Management Body of Knowledge
• Aguidi
• Aguieira Dam
• Aguie, Niger
• Aguiguan reed warbler
• Aguiguan Reed Warbler
• Aguijan
• Aguijan Reed Warbler
• Aguijan reed warbler
• Aguila Ammunition
• Aguila (artist)
• Aguila Elementary School District
• Aguilar Church (Pangasinan)
• Aguilar del Rio Alhama
• Aguilar del Río Alhama
• Aguilares
• Aguilares (disambiguation)
• Aguilares, Tucumán
• Aguilar family (Oaxacan potters)
• Aguilar, Manuel
• Aguilar-Monsalve, Luis