词条 | Toxopyrimidine |
释义 |
| ImageFile = Toxopyrimidine.svg | ImageSize = 150px | ImageAlt = | ImageFile1 = Toxopyrimidine_3D_structure.png | IUPACName = (4-Amino-2-methyl-5-pyrimidinyl)methanol | OtherNames = Pyramin[1] | Section1 = {{Chembox Identifiers | CASNo = 73-67-6 | PubChem = 777 | SMILES = Cc1ncc(c(n1)N)CO | InChI=1S/C6H9N3O/c1-4-8-2-5(3-10)6(7)9-4/h2,10H,3H2,1H3,(H2,7,8,9) | InChIKey=VUTBELPREDJDDH-UHFFFAOYSA-N | ChemSpiderID = 756 | UNII=G62V17J09J | Section2 = {{Chembox Properties | C=6 | H=9 | N=3 | O=1 | Appearance = | Density = | MeltingPt = | BoilingPt = | Solubility = | Section3 = {{Chembox Hazards | MainHazards = | FlashPt = | AutoignitionPt = }}Toxopyrimidine is a vitamin B6 antagonist with potent convulsant effects.[2][3] See also
References1. ^{{cite journal | vauthors = Haughton BG, King HK | title = Toxo-pyrimidine phosphate as an inhibitor of bacterial enzyme systems that require pyridoxal phosphate | journal = The Biochemical Journal | volume = 70 | issue = 4 | pages = 660–5 | date = December 1958 | pmid = 13607425 | pmc = 1196724 | doi = 10.1042/bj0700660 }} {{Neurotoxins}}{{Convulsants}}{{Neurotoxin-stub}}2. ^{{cite journal | vauthors = Rindi G, Ferrari G | title = The gamma-aminobutyric acid and glutamic acid content of brains of rats treated with toxopyrimidine | journal = Nature | volume = 183 | issue = 4661 | pages = 608–9 | date = February 1959 | pmid = 13632808 | doi = 10.1038/183608a0 | bibcode = 1959Natur.183..608R }} 3. ^{{cite journal | vauthors = Rindi G, Perri V, Ventura U | title = Effect of toxopyrimidine on glutamic-decarboxylase and glutamic-oxalacetic transaminase of rat brain | journal = Nature | volume = 183 | issue = 4668 | pages = 1126–7 | date = April 1959 | pmid = 13657025 | doi = 10.1038/1831126a0 | bibcode = 1959Natur.183.1126R }} 6 : Pyrimidines|Alcohols|Amines|Neurotoxins|Convulsants|Vitamin B6 antagonists |
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