词条 | Trifluoromescaline |
释义 |
| IUPAC_name = 2-[3,5-dimethoxy-4-(trifluoromethoxy)phenyl]ethanamine | image = Trifluoromescaline_structure.png | tradename = | legal_status = | routes_of_administration = | CAS_number_Ref = {{cascite|changed|??}} | CAS_number = | ATC_prefix = none | PubChem = | ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}} | ChemSpiderID = | C=11 | H=14 | F=3 | N=1 | O=3 | molecular_weight = 265.228 g/mol | smiles = COc1cc(CCN)cc(OC)c1OC(F)(F)F | StdInChI = 1S/C11H14F3NO3/c1-16-8-5-7(3-4-15)6-9(17-2)10(8)18-11(12,13)14/h5-6H,3-4,15H2,1-2H3 | StdInChIKey = AVPVNYDXWCNFJD-UHFFFAOYSA-N }}Trifluoromescaline (TF-M) is a derivative of the phenethylamine hallucinogen mescaline, which has a trifluoromethoxy group replacing the central methoxy group of mescaline. Synthesis of this compound was first reported by Daniel Trachsel in 2011, alongside many other related compounds.[1][2] Trifluoromescaline was found to be one of the most potent compounds in the series, with a reported dosage of 15-40mg (and 60mg being described as a "strong overdose"), and a slow onset of action and long duration of effects, lasting 14-24 hours or more.[3] See also
References1. ^Trachsel D. Synthese von neuen (Phenylalkyl)aminen zur Untersuchung von Struktur-Aktivitätsbeziehungen, Mitteilung 1, Mescalin Derivate. Helvetica Chimica Acta. 2002; 85(9):3019–3026. doi:10.1002/1522-2675(200209)85:9<3019::AID-HLCA3019>3.0.CO;2-4 {{Serotonergics}}{{Phenethylamines}}{{Hallucinogens}}{{hallucinogen-stub}}2. ^Trachsel D. Fluorine in psychedelic phenethylamines. Drug Testing and Analysis. Dec 2011. doi: 10.1002/dta.413 3. ^Daniel Trachsel, David Lehmann and Christoph Enzensperger. Phenethylamine Von der Struktur zur Funktion, pp 704-723. Nachtschatten Verlag AG, 2013. {{ISBN|978-3-03788-700-4}} 3 : Psychedelic phenethylamines|Serotonin receptor agonists|Trifluoromethyl compounds |
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